Evidence map›Paper›PMID 27446561›Full record

ArticleMolecular and clinical oncology2016

Cancer of unknown primary ultimately diagnosed as male breast cancer: A rare case report.

Georgios Rigakos, Amanda Vakos, Sotirios Papadopoulos, Anastasia Vernadou, Antonios Tsimpidakis, Dionysios Papachristou, Evangelia Razis

Abstract read
In one paragraph

Article in Molecular and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgios RigakosThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Amanda VakosThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Sotirios PapadopoulosThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Anastasia VernadouThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Antonios TsimpidakisThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Dionysios PapachristouThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.
Evangelia RazisThird Department of Medical Oncology, 'Hygeia' Hospital, 15123 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancers of unknown primary (CUP) constitute a significant diagnostic and therapeutic challenge for clinicians and a frequent cause of cancer-related mortality in Western countries. Immunohistochemistry assays are commonly used to identify the primary cancer, but fail in approximately one-third of cases. The identification of the possible origin of CUP is crucial, as it may help select the appropriate treatment options. We herein present the case of a 54-year-old male patient, who presented with lower back pain in June, 2013. Following a thorough investigation, the clinical and pathological findings could not identify the primary cancer, leading towards a misdiagnosis. Ultimately, microRNA testing of the resected spine lesion was able to identify the primary tumor as male breast cancer and allow for optimal treatment of the patient.

Indexed as

cancer of unknown primarymale breast cancermicroRNA profile

Identifiers

PMID27446561
PMCPMC4950128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.