ArticleFrontiers in plant science2016
ERECTA and BAK1 Receptor Like Kinases Interact to Regulate Immune Responses in Arabidopsis.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 84 citations in OpenAlex.
- An updated history of TDIF-PXY signalling: a study in cell fate and tissue patterning.The New phytologist · 2025Review
- Mastering the balance: BAK1's dual roles in steering plant growth and immunity.Horticulture research · 2025Article
- Advances in ERECTA Family Regulation of Female Gametophyte Development inPlants (Basel, Switzerland) · 2025Review
- Chemical genetics reveals cross-regulation of plant developmental signaling by the immune peptide-receptor pathway.Science advances · 2025Article
- LRR-RLK subfamily II of coreceptors: emerging, non-canonical and canonical roles in plant antiviral immunity and development.Frontiers in plant science · 2025Review
- Key mechanisms of plant-Frontiers in microbiology · 2025Review
- Chemical genetics reveals cross-activation of plant developmental signaling by the immune peptide-receptor pathway.bioRxiv : the preprint server for biology · 2024Article
- Comprehensive analysis of sesame LRR-RLKs: structure, evolution and dynamic expression profiles underFrontiers in plant science · 2024Article
- An LTR retrotransposon insertion inside CsERECTA for an LRR receptor-like serine/threonine-protein kinase results in compact (cp) plant architecture in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Receptor-like Kinases (LRR-RLKs) in Response of Plants to Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2022Review
- ERECTA regulates seed size independently of its intracellular domain via MAPK-DA1-UBP15 signaling.The Plant cell · 2022Article
- Arabidopsis ERdj3B coordinates with ERECTA-family receptor kinases to regulate ovule development and the heat stress response.The Plant cell · 2022Article
- Laying it on thick: a study in secondary growth.Journal of experimental botany · 2022Review
- Interactome of Arabidopsis Thaliana.Plants (Basel, Switzerland) · 2022Article
- Enhanced biomass and thermotolerance ofPeerJ · 2022Article
- Tomato transcriptomic response to Tuta absoluta infestation.BMC plant biology · 2021Article
- The Receptor-Like KinaseInternational journal of molecular sciences · 2021Article
- The Zygotic Division Regulator ZAR1 Plays a Negative Role in Defense AgainstFrontiers in plant science · 2021Article
- Constitutive Activation of Leucine-Rich Repeat Receptor Kinase Signaling Pathways by BAK1-INTERACTING RECEPTOR-LIKE KINASE3 Chimera.The Plant cell · 2020Article
- Plant G-protein signaling cascade and host defense.3 Biotech · 2020Review
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ERECTA (ER) receptor-like kinase (RLK) regulates Arabidopsis thaliana organ growth, and inflorescence and stomatal development by interacting with the ERECTA-family genes (ERf) paralogs, ER-like 1 (ERL1) and ERL2, and the receptor-like protein (RLP) TOO MANY MOUTHS (TMM). ER also controls immune responses and resistance to pathogens such as the bacterium Pseudomonas syringae pv. tomato DC3000 (Pto) and the necrotrophic fungus Plectosphaerella cucumerina BMM (PcBMM). We found that er null-mutant plants overexpressing an ER dominant-negative version lacking the cytoplasmic kinase domain (ERΔK) showed an enhanced susceptibility to PcBMM, suggesting that ERΔK associates and forms inactive complexes with additional RLKs/RLPs required for PcBMM resistance. Genetic analyses demonstrated that ER acts in a combinatorial specific manner with ERL1, ERL2, and TMM to control PcBMM resistance. Moreover, BAK1 (BRASSINOSTEROID INSENSITIVE 1-associated kinase 1) RLK, which together with ERf/TMM regulates stomatal patterning and resistance to Pto, was also found to have an unequal contribution with ER in regulating immune responses and resistance to PcBMM. Co-immunoprecipitation experiments in Nicotiana benthamiana further demonstrated BAK1-ER protein interaction. The secreted epidermal pattern factor peptides (EPF1 and EPF2), which are perceived by ERf members to specify stomatal patterning, do not seem to regulate ER-mediated immunity to PcBMM, since their inducible overexpression in A. thaliana did not impact on PcBMM resistance. Our results indicate that the multiproteic receptorsome formed by ERf, TMM and BAK1 modulates A. thaliana resistance to PcBMM, and suggest that the cues underlying ERf/TMM/BAK1-mediated immune responses are distinct from those regulating stomatal pattering.
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