ReviewFrontiers in psychology2016
Clinical Utility of Mindfulness Training in the Treatment of Fatigue After Stroke, Traumatic Brain Injury and Multiple Sclerosis: A Systematic Literature Review and Meta-analysis.
Review in Frontiers in psychology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of cognitive behavioral therapy in improving symptoms of fatigue in patients with stroke and multiple sclerosis: a systematic review and meta-analysis.BMC psychology · 2025Pooled it
- Education for fatigue management in people with multiple sclerosis: Systematic review and meta-analysis.European journal of neurology · 2024Pooled it
- Feasibility, Acceptability, and Efficacy of Mindfulness Training in People With Upper Motor Neuron Disorders: A Systematic Review.Archives of physical medicine and rehabilitation · 2022Pooled it
- Adjuvant therapy with Astragalus membranaceus for post-stroke fatigue: a systematic review.Metabolic brain disease · 2020Pooled it
- Impact of mindfulness-based stress reduction for people with multiple sclerosis at 8 weeks and 12 months: A randomized clinical trial.Multiple sclerosis (Houndmills, Basingstoke, England) · 2019Trial
- Fatigue relief is possible.Frontiers in integrative neuroscience · 2026Review
- Fatigue relief: the contribution of non-invasive neuromodulation (FAREviaNM).Frontiers in neuroscience · 2026Article
- Dance as an Adjunct Therapy for Neurological Rehabilitation - Creative Enrichment for Recovery (DAN-CER): Program Design and Protocol for a Mixed Methods Pilot to Assess Feasibility and Acceptability.JMIR research protocols · 2025Article
- Attention to cancer-related physical and mental fatigue: Breaking the vicious cycle.World journal of psychiatry · 2025Article
- Adaptogens in Long-Lasting Brain Fatigue: An Insight from Systems Biology and Network Pharmacology.Pharmaceuticals (Basel, Switzerland) · 2025Review
- A new mindfulness and psycho-educative program for treatment of brain fatigue, evaluated after an acquired brain injury and multiple sclerosis.Health psychology and behavioral medicine · 2025Article
- Updated Perspectives on Lifestyle Interventions as Secondary Stroke Prevention Measures: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- Managing multiple sclerosis in individuals aged 55 and above: a comprehensive review.Frontiers in immunology · 2024Review
- Patient needs and care: moves toward person-centered care for Graves' disease in Sweden.European thyroid journal · 2023Review
- The Effect of Meditation-Based Interventions on Patients with Fatigue Symptoms: A Systematic Review and Meta-Analysis.Psychologica Belgica · 2023Article
- Reference Values for the Rivermead Post-Concussion Symptoms Questionnaire (RPQ) from General Population Samples in the United Kingdom, Italy, and The Netherlands.Journal of clinical medicine · 2022Article
- The search for scientific meaning in mindfulness research: Insights from a scoping review.PloS one · 2022Article
- Psychotherapeutic Intervention for Adults With Acquired Brain Injury: A Case Study Using BackUp.Frontiers in rehabilitation sciences · 2022Article
- Effects and mechanisms of mindfulness training and physical exercise on cognition, emotional wellbeing, and brain outcomes in chronic stroke patients: Study protocol of the MindFit project randomized controlled trial.Frontiers in aging neuroscience · 2022Article
- Development of a behavioural intervention for cognitive fatigability in multiple sclerosis: Protocol for a pilot and feasibility study.Frontiers in rehabilitation sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFatigue is a common symptom following neurological illnesses and injuries, and is rated as one of the most debilitating sequela in conditions such as stroke, traumatic brain injury (TBI), and multiple sclerosis (MS). Yet effective treatments are lacking, suggesting a pressing need for a better understanding of its etiology and mechanisms that may alleviate the symptoms. Recently mindfulness-based interventions have demonstrated promising results for fatigue symptom relief.
objectiveInvestigate the efficacy of mindfulness-based interventions for fatigue across neurological conditions and acquired brain injuries. MATERIALS AND
methodsSystematic literature searches were conducted in PubMed, Medline, Web of Science, and PsycINFO. We included randomized controlled trials applying mindfulness-based interventions in patients with neurological conditions or acquired brain injuries. Four studies (N = 257) were retained for meta-analysis. The studies included patients diagnosed with MS, TBI, and stroke.
resultsThe estimated effect size for the total sample was -0.37 (95% CI: -0.58, -0.17).
conclusionThe results indicate that mindfulness-based interventions may relieve fatigue in neurological conditions such as stroke, TBI, and MS. However, the effect size is moderate, and further research is needed in order to determine the effect and improve our understanding of how mindfulness-based interventions affect fatigue symptom perception in patients with neurological conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.