Evidence map›Paper›PMID 27445776›Full record

ArticleFrontiers in human neuroscience2016

Impact of Multiple Factors on the Degree of Tinnitus Distress.

Petra Brüggemann, Agnieszka J Szczepek, Matthias Rose, Laurence McKenna, Heidi Olze, Birgit Mazurek

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  11. Tinnitus Measured in Everyday Life: A Literature Review of Ecological Momentary Assessment Studies.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Phenotypic spectrum of tinnitus patients bearing rare ANK2 gene variants.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
  16. Article
  17. Health-Related Quality of Life in Subjective, Chronic Tinnitus Patients: A Scoping Review.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Article
  18. Eavesdropping on Tinnitus Using MEG: Lessons Learned and Future Perspectives.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Petra BrüggemannTinnitus Center, Universitätsmedizin Berlin Berlin, Germany.
Agnieszka J SzczepekDepartment of Otorhinolaryngology, Universitätsmedizin Berlin Berlin, Germany.
Matthias RoseDepartment of Internal Medicine and Psychosomatics, Universitätsmedizin Berlin Berlin, Germany.
Laurence McKennaRoyal National Throat Nose and Ear Hospital, University College Hospitals London, UK.
Heidi OlzeDepartment of Otorhinolaryngology, Universitätsmedizin Berlin Berlin, Germany.
Birgit MazurekTinnitus Center, Universitätsmedizin Berlin Berlin, Germany.
Berlin Institute of Health at Charité - Universitätsmedizin Berlin · DETechnische Universität Berlin · DEKlinik für Psychosomatik · DEUniversity College Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe primary cause of subjective tinnitus is a dysfunction of the auditory system; however, the degree of distress tinnitus causes depends largely on the psychological status of the patient. Our goal was to attempt to associate the grade of tinnitus-related distress with the psychological distress, physical, or psychological discomfort patients experienced, as well as potentially relevant social parameters, through a simultaneous analysis of these factors.

methodsWe determined the level of tinnitus-related distress in 531 tinnitus patients using the German version of the tinnitus questionnaire (TQ). In addition, we used the Perceived Stress Questionnaire (PSQ); General Depression Scale Allgemeine Depression Skala (ADS), Berlin Mood Questionnaire (BSF); somatic symptoms inventory (BI), and SF-8 health survey as well as general information collected through a medical history.

resultsThe TQ score significantly correlated with a score obtained using PSQ, ADS, BSF, BI, and SF-8 alongside psychosocial factors such as age, gender, and marital status. The level of hearing loss and the auditory properties of the specific tinnitus combined with perceived stress and the degree of depressive mood and somatic discomfort of a patient were identified as medium-strong predictors of chronic tinnitus. Social factors such as gender, age, or marital status also had an impact on the degree of tinnitus distress. The results that were obtained were implemented in a specific cortical distress network model.

conclusionsUsing a large representative sample of patients with chronic tinnitus permitted a simultaneous statistical measurement of psychometric and audiological parameters in predicting tinnitus distress. We demonstrate that single factors can be distinguished in a manner that explains their causative association and influence on the induction of tinnitus-related distress.

Indexed as

multi-level analysesphysical or psychological discomfortsocial parametersthe grade of tinnitus-related distressthe psychological distress

Identifiers

PMID27445776
PMCPMC4925660
OpenAlexW2464252516

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.