ArticleFrontiers in integrative neuroscience2016
Generalized Anxiety Disorder and Social Anxiety Disorder, but Not Panic Anxiety Disorder, Are Associated with Higher Sensitivity to Learning from Negative Feedback: Behavioral and Computational Investigation.
Article in Frontiers in integrative neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Anxiety disorders and PTSD in Palestine: a literature review.BMC psychiatry · 2020Pooled it
- Studying the Digital Intervention Engagement-Mediated Relationship Between Intrapersonal Measures and Pre-Exposure Prophylaxis Adherence in Sexual and Gender Minority Youth: Secondary Analysis of a Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- The impact of state and trait general and social anxiety on theory of mind.Scientific reports · 2026Article
- "Look at me, not your screen": the negative association of parental phubbing on adolescent well-being.Frontiers in psychiatry · 2026Article
- Sleep Deprivation Induces Anxiety-like Behaviors in Mice by Impairing ApoE/AMPK/mTOR-Mediated Autophagy.Molecular neurobiology · 2025Article
- Digital measures of activity and motivation impact depression and anxiety in the real world.NPJ digital medicine · 2025Article
- Videonystamography Findings in Dizziness Patients with Background Anxiety Disorder.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Relationships between depression, anxiety, and motivation in the real-world: Effects of physical activity and screentime.medRxiv : the preprint server for health sciences · 2024Article
- Altered learning from positive feedback in adolescents with anorexia nervosa.Journal of the International Neuropsychological Society : JINS · 2024Article
- Incorporating uncertainty within dynamic interoceptive learning.Frontiers in psychology · 2024Article
- Neuropsychology of Generalized Anxiety Disorder in Clinical Setting: A Systematic Evaluation.Healthcare (Basel, Switzerland) · 2023Review
- EEG Neurofeedback for Anxiety Disorders and Post-Traumatic Stress Disorders: A Blueprint for a Promising Brain-Based Therapy.Current psychiatry reports · 2021Review
- The prevalent anxiety disorders among elementary students in Bandung, Indonesia.Journal of public health research · 2021Article
- Investigating Principal Working Memory Features in Generalized, Panic, and Social Anxiety Spectrum Disorders.Frontiers in psychiatry · 2021Article
- Transdiagnostic Phenotyping Reveals a Host of Metacognitive Deficits Implicated in Compulsivity.Scientific reports · 2020Article
- Modified Suanzaorentang Had the Treatment Effect for Generalized Anxiety Disorder for the First 4 Weeks of Paroxetine Medication: A Pragmatic Randomized Controlled Study.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Somatosensory amplification, health anxiety, and alexithymia in generalized anxiety disorder.Industrial psychiatry journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder (SAD), and panic anxiety disorder (PAD), are a group of common psychiatric conditions. They are characterized by excessive worrying, uneasiness, and fear of future events, such that they affect social and occupational functioning. Anxiety disorders can alter behavior and cognition as well, yet little is known about the particular domains they affect. In this study, we tested the cognitive correlates of medication-free patients with GAD, SAD, and PAD, along with matched healthy participants using a probabilistic category-learning task that allows the dissociation between positive and negative feedback learning. We also fitted all participants' data to a Q-learning model and various actor-critic models that examine learning rate parameters from positive and negative feedback to investigate effects of valence vs. action on performance. SAD and GAD patients were more sensitive to negative feedback than either PAD patients or healthy participants. PAD, SAD, and GAD patients did not differ in positive-feedback learning compared to healthy participants. We found that Q-learning models provide the simplest fit of the data in comparison to other models. However, computational analysis revealed that groups did not differ in terms of learning rate or exploration values. These findings argue that (a) not all anxiety spectrum disorders share similar cognitive correlates, but are rather different in ways that do not link them to the hallmark of anxiety (higher sensitivity to negative feedback); and (b) perception of negative consequences is the core feature of GAD and SAD, but not PAD. Further research is needed to examine the similarities and differences between anxiety spectrum disorders in other cognitive domains and potential implementation of behavioral therapy to remediate cognitive deficits.
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