ReviewFrontiers in neuroanatomy2016
Opposing Effects of Neuronal Activity on Structural Plasticity.
Review in Frontiers in neuroanatomy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
47 citing papers in PubMed.
- Exploring neural entrainment and synchrony in response to repeated 60 Hz flickering white light in healthy volunteers.PloS one · 2025Trial
- The deficit of oligodendrocyte family cells in layer 3 of the dorsal anterior cingulate cortex in schizophrenia: possible interactions with dysfunction and altered microanatomy.European archives of psychiatry and clinical neuroscience · 2026Article
- Functional synaptic connectivity shapes spine stability in the hippocampus.Nature communications · 2026Article
- Burst firing creates an attractor in synaptic weight dynamics.PLoS computational biology · 2026Article
- A caveat regarding the unfolding argument: implications of plasticity.Neuroscience of consciousness · 2026Article
- Reshaping reservoirs with unsupervised Hebbian adaptation.Nature communications · 2025Article
- Concept transfer of synaptic diversity from biological to artificial neural networks.Nature communications · 2025Article
- Time delays in computational models of neuronal and synaptic dynamics.Frontiers in computational neuroscience · 2025Article
- Differences in the consolidation by spontaneous and evoked ripples in the presence of active dendrites.PLoS computational biology · 2024Article
- Long ascending propriospinal neurons are heterogenous and subject to spinal cord injury induced anatomic plasticity.Experimental neurology · 2024Article
- Cellular and Molecular Mechanisms and Innovative Neurostimulation Treatments in the Management of Traumatic Brain Injury.Journal of biotechnology and biomedicine · 2024Article
- Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks.PLoS computational biology · 2023Article
- Synaptic weights that correlate with presynaptic selectivity increase decoding performance.PLoS computational biology · 2023Article
- The role of neuronal plasticity in cervical spondylotic myelopathy surgery: functional assessment and prognostic implication.Neurosurgical review · 2023Review
- Electrical stimulation methods and protocols for the treatment of traumatic brain injury: a critical review of preclinical research.Journal of neuroengineering and rehabilitation · 2023Review
- Synaptic Dysfunction and Plasticity in Amyotrophic Lateral Sclerosis.International journal of molecular sciences · 2023Review
- Biomarkers of Activity-Dependent Plasticity and Persistent Enhancement of Synaptic Transmission in Alzheimer Disease: A Review of the Current Status.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Synaptic plasticity and mental health: methods, challenges and opportunities.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Review
- Top-down and bottom-up stimulation techniques combined with action observation treatment in stroke rehabilitation: a perspective.Frontiers in neurology · 2023Review
- Dynamics of phase oscillator networks with synaptic weight and structural plasticity.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The connectivity of the brain is continuously adjusted to new environmental influences by several activity-dependent adaptive processes. The most investigated adaptive mechanism is activity-dependent functional or synaptic plasticity regulating the transmission efficacy of existing synapses. Another important but less prominently discussed adaptive process is structural plasticity, which changes the connectivity by the formation and deletion of synapses. In this review, we show, based on experimental evidence, that structural plasticity can be classified similar to synaptic plasticity into two categories: (i) Hebbian structural plasticity, which leads to an increase (decrease) of the number of synapses during phases of high (low) neuronal activity and (ii) homeostatic structural plasticity, which balances these changes by removing and adding synapses. Furthermore, based on experimental and theoretical insights, we argue that each type of structural plasticity fulfills a different function. While Hebbian structural changes enhance memory lifetime, storage capacity, and memory robustness, homeostatic structural plasticity self-organizes the connectivity of the neural network to assure stability. However, the link between functional synaptic and structural plasticity as well as the detailed interactions between Hebbian and homeostatic structural plasticity are more complex. This implies even richer dynamics requiring further experimental and theoretical investigations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.