ArticleFrontiers in neuroscience2016
Ghosts in the Machine. Interoceptive Modeling for Chronic Pain Treatment.
Article in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- [Group intervention from a sensorimotor approach to reduce the intensity of chronic pain].Atencion primaria · 2019Trial
- Toward an Embodied Medicine: A Portable Device with Programmable Interoceptive Stimulation for Heart Rate Variability Enhancement.Sensors (Basel, Switzerland) · 2018Trial
- Pain in Tourette Syndrome: A Comprehensive Review.Journal of child and adolescent psychopharmacology · 2025Review
- How Bud Craig's Insights Reshape the Research on Pain and Mind-Body Therapies.Current topics in behavioral neurosciences · 2025Review
- Attention and Interoception Alter Perceptual and Neural Pain Signatures-A Case Study.Journal of pain research · 2024Article
- How Pain Shapes Depression and Anxiety: A Hybrid Self-regulatory/Predictive Mind Perspective.Journal of clinical psychology in medical settings · 2021Review
- Osteopathy and Mental Health: An Embodied, Predictive, and Interoceptive Framework.Frontiers in psychology · 2021Article
- Altered Interoceptive Perception and the Effects of Interoceptive Analgesia in Musculoskeletal, Primary, and Neuropathic Chronic Pain Conditions.Journal of personalized medicine · 2020Article
- [Subjectivity and objectivity, illness and disease].Der Nervenarzt · 2020Article
- [Chronic pain syndromes and other persistent functional somatic symptoms].Der Nervenarzt · 2020Article
- Vagus Nerve Stimulation as a Gateway to Interoception.Frontiers in psychology · 2020Article
- Feel the Time. Time Perception as a Function of Interoceptive Processing.Frontiers in human neuroscience · 2018Article
- Emotion dysregulation as a transdiagnostic mechanism of opioid misuse and suicidality among chronic pain patients.Borderline personality disorder and emotion dysregulation · 2018Review
- Interoceptive Axes Dissociation in Anorexia Nervosa: A Single Case Study With Follow Up Post-recovery Assessment.Frontiers in psychology · 2018Article
- Embodied Medicine: Mens Sana in Corpore Virtuale Sano.Frontiers in human neuroscience · 2017Article
- Neurobiology of Anorexia Nervosa: Serotonin Dysfunctions Link Self-Starvation with Body Image Disturbances through an Impaired Body Memory.Frontiers in human neuroscience · 2016Review
- Chronic Pain and Psychiatric Conditions.Complex psychiatryReview
- Yoga for Caregiving Dyads Experiencing Chronic Pain: Protocol Development for Merging Yoga and Self-Management to Develop Skills Intervention.International journal of yogaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain is a complex and multidimensional perception, embodied in our daily experiences through interoceptive appraisal processes. The article reviews the recent literature about interoception along with predictive coding theories and tries to explain a missing link between the sense of the physiological condition of the entire body and the perception of pain in chronic conditions, which are characterized by interoceptive deficits. Understanding chronic pain from an interoceptive point of view allows us to better comprehend the multidimensional nature of this specific organic information, integrating the input of several sources from Gifford's Mature Organism Model to Melzack's neuromatrix. The article proposes the concept of residual interoceptive images (ghosts), to explain the diffuse multilevel nature of chronic pain perceptions. Lastly, we introduce a treatment concept, forged upon the possibility to modify the interoceptive chronic representation of pain through external input in a process that we call interoceptive modeling, with the ultimate goal of reducing pain in chronic subjects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.