SynthesisCanadian respiratory journal2016
Clinical Outcomes Associated with Home Mechanical Ventilation: A Systematic Review.
Synthesis in Canadian respiratory journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Experiences and support needs of patients receiving home mechanical ventilation and their caregivers: a qualitative meta-synthesis.Frontiers in public health · 2026Pooled it
- Noninvasive Home Mechanical Ventilation in Adult Myotonic Dystrophy Type 1: A Systematic Review.Respiration; international review of thoracic diseasesPooled it
- Global Research Trends in Home Mechanical Ventilation: A Bibliometric Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Usefulness of the SRespiration; international review of thoracic diseases · 2026Article
- Cost-utility analysis of home mechanical ventilation compared to hospital settings in patients with chronic obstructive pulmonary disease.Cost effectiveness and resource allocation : C/E · 2026Article
- Evaluation of factors influencing the reduction of home mechanical ventilation dependency in patients planned to receive home health care.BMC palliative care · 2026Article
- Towards clinical application of implantable brain-computer interfaces for people with late-stage ALS: medical and ethical considerations.Journal of neurology · 2023Review
- Mental health reported in adult invasive home mechanical ventilation through a tracheostomy: A scoping review.International journal of nursing studies advances · 2022Article
- Comparing the quality of care for long-term ventilated individuals at home versus in shared living communities: a convergent parallel mixed-methods study.BMC nursing · 2022Article
- Home-Based Adaptation to Night-Time Non-Invasive Ventilation in Patients with Amyotrophic Lateral Sclerosis: A Randomized Controlled Trial.Journal of clinical medicine · 2022Article
- Exploring red cell distribution width as a biomarker for treatment efficacy in home mechanical ventilation.BMC pulmonary medicine · 2022Observational
- Effect of Respiratory Events on Health-Related Quality of Life in Patients Treated with Long-Term Noninvasive Ventilation.Respiration; international review of thoracic diseases · 2022Article
- How to improve the quality of care for people on home mechanical ventilation from the perspective of healthcare professionals: a qualitative study.BMC health services research · 2021Article
- The treatment burden of long-term home noninvasive ventilation.Breathe (Sheffield, England) · 2021Article
- Cost-Utility Analysis of Home Mechanical Ventilation in Patients with Amyotrophic Lateral Sclerosis.Healthcare (Basel, Switzerland) · 2021Article
- Mortality outcomes of patients on chronic mechanical ventilation in different care settings: A systematic review.Heliyon · 2021Review
- Home mechanical ventilation: quality of life patterns after six months of treatment.BMC pulmonary medicine · 2020Observational
- Home mechanical ventilation: back to basics.Acute and critical care · 2020Article
- Telehealth: "virtual" lifeline for home-ventilated patients during the COVID-19 pandemic.ERJ open research · 2020Article
- Validation of the Hungarian version of the SRI Questionnaire.BMC pulmonary medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. The prevalence of patients supported with home mechanical ventilation (HMV) for chronic respiratory failure has increased. However, the clinical outcomes associated with HMV are largely unknown. Methods. We performed a systematic review of studies evaluating patients receiving HMV for indications other than obstructive lung disease, reporting at least one clinically relevant outcome including health-related quality of life (HRQL) measured by validated tools; hospitalization requirements; caregiver burden; and health service utilization. We searched MEDLINE, EMBASE, CINAHL, the Cochrane library, clinical trial registries, proceedings from selected scientific meetings, and bibliographies of retrieved citations. Results. We included 1 randomized control trial (RCT) and 25 observational studies of mixed methodological quality involving 4425 patients; neuromuscular disorders (NMD) (n = 1687); restrictive thoracic diseases (RTD) (n = 481); obesity hypoventilation syndrome (OHS) (n = 293); and others (n = 748). HRQL was generally described as good for HMV users. Mental rather than physical HRQL domains were rated higher, particularly where physical assessment was limited. Hospitalization rates and days in hospital appear to decrease with implementation of HMV. Caregiver burden associated with HMV was generally high; however, it is poorly described. Conclusion. HRQL and need for hospitalization may improve after establishment of HMV. These inferences are based on relatively few studies of marked heterogeneity and variable quality.
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