Evidence map›Paper›PMID 27445555›Full record

ArticleCanadian respiratory journal2016

The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario.

Haris M Vaid, Ximena Camacho, John T Granton, Muhammad M Mamdani, Zhan Yao, Samantha Singh, David N Juurlink, Tara Gomes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian respiratory journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Management of pulmonary hypertension in special conditions.The European respiratory journal · 2024
    Review
  2. Article
  3. Sex and gender in pulmonary arterial hypertension.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Haris M VaidSchool of Medicine, Queen's University, 15 Arch Street, Kingston, ON, Canada K7L 3N6.
Ximena CamachoThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5.
John T GrantonToronto General Hospital, 200 Elizabeth Street, Toronto, ON, Canada M5G 2C4; University Health Network, 399 Bathurst Street, Toronto, ON, Canada M5T 2S8; Department of Medicine, The University of Toronto, 1 King's College Circle No. 3172, Toronto, ON, Canada M5S 1A8.
Muhammad M MamdaniThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5; Department of Medicine, The University of Toronto, 1 King's College Circle No. 3172, Toronto, ON, Canada M5S 1A8; The Department of Medicine, St. Michael's Hospital, 30 Bond Street, Toronto, ON, Canada M5B 1W8; Department of Health Policy, Management, and Evaluation, The University of Toronto, 155 College Street, Toronto, ON, Canada M5T 3M6; The Leslie Dan Faculty of Pharmacy, The University of Toronto, 144 College Street, Toronto, ON, Canada M5S 3M2; Keenan Research Centre, The Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.
Zhan YaoThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5.
Samantha SinghThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5.
David N JuurlinkThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5; Department of Medicine, The University of Toronto, 1 King's College Circle No. 3172, Toronto, ON, Canada M5S 1A8; Department of Health Policy, Management, and Evaluation, The University of Toronto, 155 College Street, Toronto, ON, Canada M5T 3M6; The Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5; Department of Pediatrics, The University of Toronto, 555 University Avenue Black Wing, 1436 Toronto, ON, Canada M5G 1X8.
Tara GomesThe Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G1 06, Toronto, ON, Canada M4N 3M5; Department of Health Policy, Management, and Evaluation, The University of Toronto, 155 College Street, Toronto, ON, Canada M5T 3M6; The Leslie Dan Faculty of Pharmacy, The University of Toronto, 144 College Street, Toronto, ON, Canada M5S 3M2; Keenan Research Centre, The Li Ka Shing Knowledge Institute, St. Michael's Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. There are no Canadian prevalence studies on pulmonary arterial hypertension (PAH) to date. We described the characteristics of treated PAH patients and the healthcare utilization and costs associated with PAH in a population of public drug plan beneficiaries in Ontario, Canada. Methods. A retrospective cross-sectional analysis was conducted between April 2010 and March 2011 to identify treated PAH patients using population-based health administrative databases. We investigated demographic and clinical characteristics of treated PAH patients and conducted a cohort study to determine treatment patterns, healthcare utilization, and associated costs, over a one-year follow-up period (March 2012). Results. We identified 326 treated PAH cases in Ontario's publicly funded drug plan. Overall mean age was 59.4 years (±20.3 years) and over 77% of cases were women (n = 251). Combination therapy was used to treat 22.9% (n = 69) of cases, costing an average of $4,569 (SD $1,544) per month. Median monthly healthcare costs were $264 (IQR $96-$747) for those who survived and $2,021 (IQR $993-$6,399) for those who died over a one-year period, respectively (p < 0.01). Conclusions. PAH care in Ontario is complex and has high healthcare costs. This data may help guide towards improved patient management.

Indexed as

AdultAgedAged, 80 and overCosts and Cost AnalysisCross-Sectional StudiesEndothelin Receptor AntagonistsFemaleHealth ServicesHumansHypertension, PulmonaryMaleMiddle AgedOntarioEndothelin Receptor Antagonists

Identifiers

PMID27445555
PMCPMC4904539

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.