ArticleClinical interventions in aging2016
Assessment risk of osteoporosis in Chinese people: relationship among body mass index, serum lipid profiles, blood glucose, and bone mineral density.
Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- The association between body mass index and osteoporosis, with consideration of sex differences: a systematic review and dose-response meta-analysis.BMC musculoskeletal disorders · 2026Pooled it
- Prevalence of osteoporosis and incidence of related fractures in developed economies in the Asia Pacific region: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2021Pooled it
- Missed Opportunities in Osteoporosis Prevention and Screening in Postmenopausal Women: Risk Profiles and AwarenessTurkish journal of pharmaceutical sciences · 2026Article
- Article
- The hidden influence of type 2 diabetes on bone mineral density across the lifespan: a Mendelian randomization study.Hormones (Athens, Greece) · 2025Article
- Impact of anti-osteoporotic treatments on hyperlipidemia risk in osteoporosis patients: evidence from a population-based retrospective cohort study.European journal of medical research · 2025Article
- NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27-Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss.FASEB bioAdvances · 2025Article
- [Analysis of demographic and clinical characteristics of 744 inpatients with osteoporotic vertebral compression fractures].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Correlation between serum high-density lipoprotein cholesterol and bone mineral density in vitamin D-deficient populations.Journal of bone and mineral metabolism · 2025Article
- Fracture Risk Assessment in Metabolic Syndrome in Terms of Secondary Osteoporosis Potential. A Narrative Review.Calcified tissue international · 2025Review
- Abnormally low serum albumin levels are associated with abnormal bone mineral density and osteoporotic fractures: a retrospective studies.BMC musculoskeletal disorders · 2024Article
- Feasibility study of opportunistic osteoporosis screening on chest CT using a multi-feature fusion DCNN model.Archives of osteoporosis · 2024Article
- Article
- Non-linear association of atherogenic index of plasma with bone mineral density a cross-sectional study.Lipids in health and disease · 2024Article
- Association of Decreased Bone Density and Hyperlipidemia in a Taiwanese Older Adult Population.Journal of the Endocrine Society · 2024Article
- Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index.BMC musculoskeletal disorders · 2024Article
- Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study.Lipids in health and disease · 2024Article
- The impact of diabetes, anemia, and renal function in the relationship between osteoporosis and fasting blood glucose among Taiwanese women: a cross-sectional study.BMC women's health · 2024Article
- Cardiometabolic index is associated with increased bone mineral density: a population-based cross-sectional study.Frontiers in public health · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of our study was to investigate the relationship among age, sex, body mass index (BMI), serum lipid profiles, blood glucose (BG), and bone mineral density (BMD), making an assessment of the risk of osteoporosis. MATERIALS AND
methodsA total of 1,035 male and 3,953 female healthy volunteers (aged 41-95 years) were recruited by an open invitation. The basic information, including age, sex, height, weight, waistline, hipline, menstrual cycle, and medical history, were collected by a questionnaire survey and physical examination. Serum lipid profiles, BG, postprandial blood glucose, and glycosylated hemoglobin were obtained after 12 hours fasting. BMD in lumbar spine was measured by dual-energy X-ray absorptiometry scanning.
resultsThe age-adjusted BMD in females was significantly lower than in males. With aging, greater differences of BMD distribution exist in elderly females than in males (P<0.001), and the fastigium of bone mass loss was in the age range from 51 to 55 in females and from 61 to 65 years in males. After adjustment for sex, there were significant differences in BMD among BMI-stratified groups in both males and females. The subjects with a BMI of <18.5 had a higher incidence of osteoporosis than BMI ≥18.5 in both sexes. BMD in type 2 diabetes mellitus with a BG of >7.0 mmol/L was lower than in people with BG of ≤7.0 mmol/L (P<0.001). People with serum high-density lipoprotein cholesterol levels of ≥1.56 mmol/L had a greater prevalence of osteoporosis compared with high-density lipoprotein cholesterol ≤1.55 mmol/L. Logistic regression with odds ratios showed that no association was found among total cholesterol, triglyceride, low-density lipoprotein cholesterol, glycosylated hemoglobin, postprandial blood glucose and BMD.
conclusionThe present study further confirmed that factors such as age, sex, weight, BMI, high-density lipoprotein cholesterol, and diabetes are significant predictors of osteoporosis in the Chinese people.
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