ArticleChest2016
Where You Live Matters: The Impact of Place of Residence on Severe Sepsis Incidence and Mortality.
Article in Chest, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Trends and Disparities in Post-acute Care Utilization After Hospitalization for Sepsis in the United States: A Systematic Review.Medical care · 2026Pooled it
- Rapid systematic review on risks and outcomes of sepsis: the influence of risk factors associated with health inequalities.International journal for equity in health · 2024Pooled it
- Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis.Intensive care medicine · 2020Pooled it
- Health Disparities and Sepsis: a Systematic Review and Meta-Analysis on the Influence of Race on Sepsis-Related Mortality.Journal of racial and ethnic health disparities · 2019Pooled it
- Association Between Community-Level Social Determinants of Health and Sepsis Incidence and Mortality: A Scoping Review.Critical care explorations · 2026Article
- Trends in sepsis-related mortality due to dermatologic infections in the United States: Demographic and geographic patterns from 1999 to 2023.Journal of public health research · 2026Article
- The Global Impact of Sepsis: Epidemiology, Recognition, Management, and Health System Challenges.Epidemiologia (Basel, Switzerland) · 2026Review
- Mitigating Bias in Machine Learning Models with Ethics-Based Initiatives: The Case of Sepsis.The American journal of bioethics : AJOB · 2026Article
- The incidence and risk factors of sepsis following ovarian cancer surgery: A retrospective Nationwide Inpatient Sample database study.PloS one · 2026Article
- Article
- Factors Associated with Health Service Use for Self-Reported Balance Problems in Community-Dwelling Adults: A Secondary Analysis of Nationally Representative NHANES 2001-2004 Data.Healthcare (Basel, Switzerland) · 2025Article
- Examining socioeconomic differences in sepsis risk and mediation by modifiable factors: a Mendelian randomization study.BMC infectious diseases · 2025Article
- Social determinants of health and sepsis: a case-control study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Article
- The Global Burden of Sepsis and Septic Shock.Epidemiologia (Basel, Switzerland) · 2024Review
- Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States.Journal of clinical medicine · 2024Article
- The role of place-based factors and other social determinants of health on adverse post-sepsis outcomes: a review of the literature.Frontiers in disaster and emergency medicine · 2024Article
- Clinical and health inequality risk factors for non-COVID-related sepsis during the global COVID-19 pandemic: a national case-control and cohort study.EClinicalMedicine · 2023Article
- Potential Factors Associated with Healthcare Utilization for Balance Problems in Community-Dwelling Adults within the United States: A Narrative Review.Healthcare (Basel, Switzerland) · 2023Review
- Neighborhood socioeconomic deprivation, healthcare access, and 30-day mortality and readmission after sepsis or critical illness: findings from a nationwide study.Critical care (London, England) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundMedically underserved areas are composed of vulnerable populations with reduced access to ambulatory care services. Our goal was to determine the association between residence in a medically underserved area and severe sepsis incidence and mortality.
methodsUsing administrative data, we identified adults admitted with severe sepsis to nonfederal hospitals in South Carolina. We determined whether each resident lived in a medically underserved area or nonmedically underserved area from US Census and Department of Health and Human Services data. Age-adjusted severe sepsis incidence and mortality rates were calculated and compared between both residential classifications. Multivariate logistic regression measured the association between residence in a medically underserved area and mortality while adjusting for confounders.
resultsIn 2010, 24,395 adults were admitted with severe sepsis and 1,446,987 (43%) adults lived in a medically underserved area. Residents of medically underserved areas were admitted more frequently with severe sepsis (8.6 vs 6.8 cases/1,000 people, P < .01) and were more likely to die (15.5 vs 11.9 deaths/10,000 people, P < .01), with increased odds of severe sepsis-related death (OR, 1.12) after adjustment for age, race, and severity of illness. ZIP code-based surrogates of socioeconomic status, including median income, proportion below poverty level, and educational attainment, however, had minimal association with sepsis mortality.
conclusionsResidence in a medically underserved area is associated with higher incidence and mortality rates of severe sepsis and represents a novel method of access-to-care adjustment. Traditional access-to-care surrogates, however, are poorly associated with sepsis mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.