ArticleScientific reports2016
The occurrence of individual slow waves in sleep is predicted by heart rate.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Cardio-audio synchronization elicits neural and cardiac surprise responses in human wakefulness and sleep.Communications biology · 2024Article
- Effect of Propofol on Heart Rate and Its Coupling to Cortical Slow Waves in Humans.Anesthesiology · 2024Article
- fMRI spectral signatures of sleep.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Imaging the temporal dynamics of brain states with highly sampled fMRI.Current opinion in behavioral sciences · 2021Article
- The Challenges and Pitfalls of Detecting Sleep Hypopnea Using a Wearable Optical Sensor: Comparative Study.Journal of medical Internet research · 2021Article
- Error Assessment and Mitigation Methods in Transient Radar Method.Sensors (Basel, Switzerland) · 2020Article
- Oscillating circuitries in the sleeping brain.Nature reviews. Neuroscience · 2019Review
- Sleep stage classification from heart-rate variability using long short-term memory neural networks.Scientific reports · 2019Article
- The Human Default Consciousness and Its Disruption: Insights From an EEG Study of Buddhist Jhāna Meditation.Frontiers in human neuroscience · 2019Article
- Coupling of autonomic and central events during sleep benefits declarative memory consolidation.Neurobiology of learning and memory · 2019Article
- Pupil Size Coupling to Cortical States Protects the Stability of Deep Sleep via Parasympathetic Modulation.Current biology : CB · 2018Article
- The Comparisons of Cerebral Hemodynamics Induced by Obstructive Sleep Apnea with Arousal and Periodic Limb Movement with Arousal: A Pilot NIRS Study.Frontiers in neuroscience · 2016Article
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The integration of near-infrared spectroscopy and electroencephalography measures presents an ideal method to study the haemodynamics of sleep. While the cortical dynamics and neuro-modulating influences affecting the transition from wakefulness to sleep is well researched, the assumption has been that individual slow waves, the hallmark of deep sleep, are spontaneously occurring cortical events. By creating event-related potentials from the NIRS recording, time-locked to the onset of thousands of individual slow waves, we show the onset of slow waves is phase-locked to an ongoing oscillation in the NIRS recording. This oscillation stems from the moment to moment fluctuations of light absorption caused by arterial pulsations driven by the heart beat. The same oscillating signal can be detected if the electrocardiogram is time-locked to the onset of the slow wave. The ongoing NIRS oscillation suggests that individual slow wave initiation is dependent on that signal, and not the other way round. However, the precise causal links remain speculative. We propose several potential mechanisms: that the heart-beat or arterial pulsation acts as a stimulus which evokes a down-state; local fluctuations in energy supply may lead to a network effect of hyperpolarization; that the arterial pulsations lead to corresponding changes in the cerebral-spinal-fluid which evokes the slow wave; or that a third neural generator, regulating heart rate and slow waves may be involved.
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