Evidence map›Paper›PMID 27444618›Full record

ArticleJournal of endocrinological investigation2016

Relationship of galectin-3 with obesity, IL-6, and CRP in women.

J Pang, V T Nguyen, D H Rhodes, M E Sullivan, C Braunschweig, G Fantuzzi

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

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  8. Galectin-3 levels in children with cystic fibrosis.European journal of pediatrics · 2024
    Article
  9. Galectin-3, Metabolic Risk, and Incident Heart Failure: The ARIC Study.Journal of the American Heart Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J PangDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA.
V T NguyenDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA.
D H RhodesDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA.
M E SullivanDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA.
C BraunschweigDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA.
G FantuzziDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL, 60612, USA. giamila@uic.edu.
University of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the association of galectin-3 (Gal3) with obesity and inflammatory status in a cohort of metabolically healthy, predominantly African-American women with varying cardiovascular disease (CVD) risk as determined by CRP levels.

methodsWe assessed the association between BMI and serum levels of Gal3, IL-6, CRP, and adiponectin in metabolically healthy women (N = 97) to determine the overall association between Gal3, obesity, and inflammation in groups at different CVD risk.

resultsObese women had significantly higher serum Gal3 compared to non-obese participants (P = 0.0016), although Gal3 levels were comparable among different classes of obesity. BMI (R

conclusionsGal3 is positively correlated with obesity and inflammation in women, while the presence of elevated CVD risk may disturb the strength of Gal3 as a biomarker of inflammation.

Indexed as

AdiposityAdultBiomarkersCardiovascular DiseasesCase-Control StudiesC-Reactive ProteinFemaleGalectin 3HumansInflammationInterleukin-6ObesityRisk FactorsBiomarkersC-Reactive ProteinGalectin 3Interleukin-6CRPCytokinesInflammationObesityWomen

Identifiers

PMID27444618
OpenAlexW2484796437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.