Evidence map›Paper›PMID 27444428›Full record

Trial reportContemporary clinical trials2016

Integrating tobacco treatment into cancer care: Study protocol for a randomized controlled comparative effectiveness trial.

Elyse R Park, Jamie S Ostroff, Giselle K Perez, Kelly A Hyland, Nancy A Rigotti, Sarah Borderud, Susan Regan, Alona Muzikansky, Emily R Friedman, Douglas E Levy and 10 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. A qualitative study of attitudes and perceptions of smoking cessation medication among patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  4. Longitudinal Electronic Cigarette Use Among Patients Recently Diagnosed With Cancer Enrolled in a Smoking Cessation Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
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  9. A smoking cessation and pain management program for cancer survivors.Journal of cancer survivorship : research and practice · 2018
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Elyse R ParkMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States; Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, United States; Cancer Outcomes Research Program, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States; Benson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, MA, United States; Department of Medicine, Harvard Medical School, Boston, MA, United States. Electronic address: epark@mgh.harvard.edu.
Jamie S OstroffDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: ostroffj@mskcc.org.
Giselle K PerezMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States; Cancer Outcomes Research Program, Massachusetts General Hospital, Boston, MA, United States; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States. Electronic address: gperez@mgh.harvard.edu.
Kelly A HylandH. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL, United States. Electronic address: khyland@mail.usf.edu.
Nancy A RigottiMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States; Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston, MA, United States; Department of Medicine, Harvard Medical School, Boston, MA, United States. Electronic address: nrigotti@partners.org.
Sarah BorderudDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: borderus@mskcc.org.
Susan ReganMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States. Electronic address: sregan@mgh.harvard.edu.
Alona MuzikanskyBiostatistics Center, Massachusetts General Hospital, Boston, MA, United States. Electronic address: amuzikansky@mgh.harvard.edu.
Emily R FriedmanMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States; Cancer Outcomes Research Program, Massachusetts General Hospital, Boston, MA, United States. Electronic address: erfriedman@mgh.harvard.edu.
Douglas E LevyMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States. Electronic address: dlevy3@mgh.harvard.edu.
Susan HollandDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: hollands@mskcc.org.
Justin EusebioCancer Outcomes Research Program, Massachusetts General Hospital, Boston, MA, United States. Electronic address: jeusebio@mgh.harvard.edu.
Lisa PetersonDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: petersol@mskcc.org.
Julia RabinMongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, United States; Cancer Outcomes Research Program, Massachusetts General Hospital, Boston, MA, United States. Electronic address: jtrabin@mgh.harvard.edu.
Jacob Miller-SobelDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: millersj@mskcc.org.
Irina GonzalezDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, United States. Electronic address: igonzalez4@mgh.harvard.edu.
Laura MalloyBenson-Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, MA, United States. Electronic address: lmalloy@mgh.harvard.edu.
Maureen O'BrienDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: obrienm@mskcc.org.
Suhana de León-SanchezDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: deleonss@mskcc.org.
C Will WhitlockDepartment of Psychiatry & Behavioral Sciences, Tobacco Treatment Program, Memorial Sloan Kettering Cancer Center, New York, NY, United States. Electronic address: whitlocc@mskcc.org.
Memorial Sloan Kettering Cancer Center · USMassachusetts General Hospital · USMGH Institute of Health Professions · USHarvard University · USMoffitt Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Integrating Tobacco Treatment into Cancer CareR01CA166147 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2012 to 2016
$3.6M
Examining Delivery of Integrated Tobacco Treatment in Cancer CareK24CA197382 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PARK, ELYSE R. · 2015 to 2019
$841k
NCI NIH HHS K24 CA197382NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA166147
6 · The paper itself

Abstract

backgroundDespite the well-established risks of persistent smoking, 10-30% of cancer patients continue to smoke after diagnosis. Evidence-based tobacco treatment has yet to be integrated into routine oncology care. This paper describes the protocol, manualized treatment, evaluation plan, and overall study design of comparing the effectiveness and cost of two treatments across two major cancer centers. METHODS/

designA two-arm, two-site randomized controlled comparative effectiveness trial is testing the hypothesis that an Intensive Treatment (IT) intervention is more effective than a Standard Treatment (ST) intervention in helping recently diagnosed cancer patients quit smoking. Both interventions include 4 weekly counseling sessions and FDA-approved smoking cessation medication advice. The IT includes an additional 4 biweekly and 3 monthly booster sessions as well as dispensal of the recommended FDA-approved smoking cessation medication at no cost. The trial is enrolling patients with suspected or newly diagnosed cancer who have smoked a cigarette in the past 30days. Participants are randomly assigned to receive the ST or IT condition. Tobacco cessation outcomes are assessed at 3 and 6months. The primary study outcome is 7-day point prevalence biochemically-validated tobacco abstinence. Secondary study outcomes include the incremental cost-effectiveness of the IT vs. ST. DISCUSSION: This trial will answer key questions about delivering tobacco treatment interventions to newly diagnosed cancer patients. If found to be efficacious and cost-effective, this treatment will serve as a model to be integrated into oncology care settings nation-wide, as we strive to improve treatment outcomes and quality of life for cancer patients.

Indexed as

Tobacco Use Cessation DevicesCancer Care FacilitiesComparative Effectiveness ResearchCost-Benefit AnalysisCounselingEmotionsEnvironmentFemaleHealth Knowledge, Attitudes, PracticeHumansMaleNeoplasmsQuality of LifeResearch DesignSmoking CessationSocioeconomic FactorsCancer patientsMotivational interviewingPharmacotherapyRandomized controlled trialSmoking cessationTobacco treatment

Identifiers

PMID27444428
PMCPMC5035625
OpenAlexW2477124836

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.