Evidence map›Paper›PMID 27443593›Full record

ArticleVaccine2016

Measuring indirect effects of rotavirus vaccine in low income countries.

Aisleen Bennett, Naor Bar-Zeev, Nigel A Cunliffe

Abstract read
In one paragraph

Article in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aisleen BennettMalawi-Liverpool-Wellcome Trust Clinical Research Programme, P.O Box 30960, Chichiri, Blantyre 3, Malawi; Institute of Infection & Global Health, University of Liverpool, 8 West Derby Street, Liverpool L69 7BE, UK.
Naor Bar-ZeevMalawi-Liverpool-Wellcome Trust Clinical Research Programme, P.O Box 30960, Chichiri, Blantyre 3, Malawi; Institute of Infection & Global Health, University of Liverpool, 8 West Derby Street, Liverpool L69 7BE, UK.
Nigel A CunliffeMalawi-Liverpool-Wellcome Trust Clinical Research Programme, P.O Box 30960, Chichiri, Blantyre 3, Malawi; Institute of Infection & Global Health, University of Liverpool, 8 West Derby Street, Liverpool L69 7BE, UK. Electronic address: n.a.cunliffe@liv.ac.uk.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Widespread introduction of rotavirus vaccines has led to major reductions in the burden of rotavirus gastroenteritis worldwide. Vaccine effectiveness is diminished, however, in low income countries, that harbour the greatest burden of rotavirus attributed morbidity and mortality. Indirect effects of rotavirus vaccine (herd immunity and herd protection) could increase population level impact and improve vaccine cost effectiveness in such settings. While rotavirus vaccine indirect effects have been demonstrated in high and middle income countries, there are very little data from low income countries where force of infection, population structures and vaccine schedules differ. Targeted efforts to evaluate indirect effects of rotavirus vaccine in low income countries are required to understand the total impact of rotavirus vaccine on the global burden of rotavirus disease.

Indexed as

Developing CountriesCost-Benefit AnalysisCost of IllnessGastroenteritisHumansImmunity, HerdRotavirus InfectionsRotavirus VaccinesRotavirus VaccinesGastroenteritisHerd effectsRotavirusVaccine

Identifiers

PMID27443593
PMCPMC5047945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.