ArticleScientific reports2016
Mitonuclear interactions, mtDNA-mediated thermal plasticity, and implications for the Trojan Female Technique for pest control.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Review
- G × G × E effect on phenotype expression in a non-conventional model organism, the unicellular slime mouldBiology letters · 2023Article
- Editorial: Precision control technology and application in agricultural pest and disease control.Frontiers in plant science · 2023Article
- Investigating the Impact of a Curse: Diseases, Population Isolation, Evolution and the Mother's Curse.Genes · 2022Review
- Effects of mitochondrial haplotype on pre-copulatory mating success in male fruit flies (Drosophila melanogaster).Journal of evolutionary biology · 2022Article
- Decoding the rosetta stone of mitonuclear communication.Pharmacological research · 2020Review
- An evolutionary, or "Mitocentric" perspective on cellular function and disease.Redox biology · 2020Review
- Genetic Biocontrol for Invasive Species.Frontiers in bioengineering and biotechnology · 2020Review
- High incidence of heteroplasmy in the mtDNA of a natural population of the spider crab Maja brachydactyla.PloS one · 2020Article
- Experimental evidence that thermal selection shapes mitochondrial genome evolution.Scientific reports · 2018Article
- Mitochondrial genetic effects on reproductive success: signatures of positive intrasexual, but negative intersexual pleiotropy.Proceedings. Biological sciences · 2018Article
- Coadaptation of mitochondrial and nuclear genes, and the cost of mother's curse.Proceedings. Biological sciences · 2018Article
- Article
- No effect of mitochondrial genotype on reproductive plasticity following exposure to a non-infectious pathogen challenge in female or male Drosophila.Scientific reports · 2017Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pest species pose major challenges to global economies, ecosystems, and health. Unfortunately, most conventional approaches to pest control remain costly, and temporary in effect. As such, a heritable variant of the Sterile Insect Technique (SIT) was proposed, based on the introduction of mitochondrial DNA mutations into pest populations, which impair male fertility but have no effects on females. Evidence for this "Trojan Female Technique" (TFT) was recently provided, in the form of a mutation in the mitochondrial cytochrome b gene (mt:Cyt-b) of Drosophila melanogaster which reduces male fertility across diverse nuclear backgrounds. However, recent studies have shown that the magnitude of mitochondrial genetic effects on the phenotype can vary greatly across environments, with mtDNA polymorphisms commonly entwined in genotype-by-environment (G × E) interactions. Here we test whether the male-sterilizing effects previously associated with the mt:Cyt-b mutation are consistent across three thermal and three nuclear genomic contexts. The effects of this mutation were indeed moderated by the nuclear background and thermal environment, but crucially the fertility of males carrying the mutation was invariably reduced relative to controls. This mutation thus constitutes a promising candidate for the further development of the TFT.
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