Evidence map›Paper›PMID 27443273›Full record

ArticleJournal of the International AIDS Society2016

Assessment of linkages from HIV testing to enrolment and retention in HIV care in Central Mozambique.

Celso Azarias Inguane, Stephen Gloyd, João Luis Manuel, Charlene Brown, Vincent Wong, Orvalho Augusto, Wisal Mustafa Hassan, Lúcia Vieira, Pires Afonso, Mehol Jamnadás and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Celso Azarias InguaneDepartment of Anthropology, University of Washington, Seattle, WA, USA.
Stephen GloydHealth Alliance International, Seattle, WA, USA.
João Luis ManuelCentro de Investigação Operacional de Beira (CIOB), Ministry of Health, Beira, Mozambique.
Charlene BrownOffice of HIV/AIDS, USA, Agency for International Development, Washington, DC, USA.
Vincent WongOffice of HIV/AIDS, USA, Agency for International Development, Washington, DC, USA.
Orvalho AugustoHealth Alliance International, Seattle, WA, USA.
Wisal Mustafa HassanHealth Alliance International, Seattle, WA, USA.
Lúcia VieiraCentro de Investigação Operacional de Beira (CIOB), Ministry of Health, Beira, Mozambique.
Pires AfonsoHealth Alliance International, Seattle, WA, USA.
Mehol JamnadásCentro de Investigação Operacional de Beira (CIOB), Ministry of Health, Beira, Mozambique.
Jama Joy BernardHealth Alliance International, Seattle, WA, USA.
James CowanHealth Alliance International, Seattle, WA, USA.
Samuel KalibalaHIVCore/Population Council, Washington, DC, USA.
James PfeifferHealth Alliance International, Seattle, WA, USA.
Health Alliance International · USMinistry of Health · MZUnited States Agency for International Development · USUniversity of Washington · USZero to Three · USPopulation Council · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
NIAID NIH HHS P30 AI027757PEPFAR
6 · The paper itself

Abstract

introductionEffectiveness of the rapid expansion of antiretroviral therapy (ART) throughout sub-Saharan Africa is highly dependent on adequate enrolment and retention in HIV care. However, the measurement of both has been challenging in these settings. This study aimed to assess enrolment and retention in HIV care (pre-ART and ART) among HIV-positive adults in Central Mozambique, including identification of barriers and facilitators.

methodsWe assessed linkages to and retention in HIV care using a mixed quantitative and qualitative approach in six districts of Manica and Sofala provinces. We analyzed routine district and health facility monthly reports and HIV care registries from April 2012 to March 2013 and used single imputation and trimmed means to adjust for missing values. In eight health facilities in the same districts and period, we assessed retention in HIV care among 795 randomly selected adult patient charts (15 years and older). We also conducted 25 focus group discussions and 53 in-depth interviews with HIV-positive adults, healthcare providers and community members to identify facilitators and barriers to enrolment and retention in HIV care.

resultsOverall, 46% of the monthly HIV testing reports expected at the district level were missing, compared to 6.4% of the pre-ART registry reports. After adjustment for missing values, we estimated that the aggregate numbers of adults registered in pre-ART was 75% of the number of persons tested HIV-positive in the six districts. In the eight health facilities, 40% of the patient charts for adults enrolled in pre-ART and 44% in ART were missing. Of those on ART for whom charts were found, retention in treatment within 90 and 60 days prior to the study team visit was 34 and 25%, respectively. Combining these multiple data sources, the overall estimated retention was 18% in our sample. Individual-level factors were perceived to be key influences to enrolment in HIV care, while health facility and structural-level factors were perceived to be key influences of retention.

conclusionsEfforts to increase linkages to and retention in HIV care should address individual, health facility, and structural-level factors in Central Mozambique. However, their outcomes cannot be reliably assessed without improving the quality of routine health information systems.

Indexed as

Delivery of Health CarePatient Acceptance of Health CareAdolescentAdultFemaleFocus GroupsHealth FacilitiesHIV InfectionsHumansMaleMass ScreeningMozambiqueResidence CharacteristicsYoung AdultHIV carelinkagesMozambiqueretentiontreatment

Identifiers

PMID27443273
PMCPMC4956731
OpenAlexW2505318394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.