Evidence map›Paper›PMID 27442424›Full record

SynthesisPloS one2016

Methicillin-Resistant Staphylococcus aureus Nasal Colonization in Chinese Children: A Prevalence Meta-Analysis and Review of Influencing Factors.

Jialing Lin, Yang Peng, Ping Xu, Ting Zhang, Chan Bai, Dongxin Lin, Qianting Ou, Zhenjiang Yao

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Characterisation of nasopharyngeal colonisation byBMJ open respiratory research · 2025
    Article
  3. Article
  4. International journal of molecular sciences · 2022
    Review
  5. Article
  6. Article
  7. Nasal Methicillin-ResistantMicroorganisms · 2021
    Article
  8. Article
  9. Article
  10. Infection and drug resistance · 2020
    Article
  11. Article
  12. Prevalence of Cefepime-ResistantIranian journal of public health · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jialing LinDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Yang PengCentre for Chronic Disease, University of Queensland, Brisbane, Australia.
Ping XuDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Ting ZhangDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Chan BaiDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Dongxin LinDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Qianting OuDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Zhenjiang YaoDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou, China.
Guangdong Pharmaceutical University · CNUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the pooled prevalence and review the influencing factors of methicillin-resistant Staphylococcus aureus (MRSA) nasal colonization in Chinese children.

methodsArticles published between January 2005 and October 2015 that studied prevalence or influencing factors of MRSA nasal colonization in Chinese children were retrieved from Chinese Biomedical Literature database (CBM), China National Knowledge Infrastructure (CNKI) database, Chinese VIP database, Chinese Wanfang database, Medline database and Ovid database. Prevalence and influencing factors were analyzed by STATA 13.1.

resultsThirteen articles were included. The overall prevalence of MRSA nasal colonization was 4.4% (95% confidence interval [CI]: 0.027-0.062). With an MRSA prevalence of 3.9% (95% CI: 0.018-0.061) in healthy children and 5.8% (95% CI: 0.025-0.092) in children with underlying medical conditions. Children recruited in the hospitals presented MRSA prevalence of 6.4% (95% CI: 0.037-0.091), which was higher than those recruited in the communities [2.7% (95% CI: 0.012-0.043)]. A number of influencing factors for MRSA nasal colonization were noted in three eligible studies: gender (male vs female; OR: 0.67; 95% CI: 0.55-0.82), younger age (OR: 2.98; 95% CI: 1.31-6.96 and OR: 1.56; 95% CI: 1.21-2.00), attending day care centers (OR: 2.97; 95% CI: 1.28-6.76), having infectious diseases (OR: 2.31; 95% CI: 1.10-4.52), using antibiotics (OR: 2.77; 95% CI: 1.45-5.05), residing in northern Taiwan (OR: 1.41; 95% CI: 1.15-1.71), passive smoking (OR: 1.30; 95% CI: 1.02-1.63), and pneumococcal vaccination (OR: 1.22; 95% CI: 1.01-1.48).

conclusionsChildren could act as reservoirs of MRSA transmissions. Hospitals remained the most frequent microorganism-circulated settings. More MRSA infection control strategies are required to prevent the dissemination among children.

Indexed as

Methicillin-Resistant Staphylococcus aureusAge FactorsCarrier StateChildDatabases, FactualFemaleHumansMaleNasal MucosaOdds RatioPopulation SurveillancePrevalencePublication BiasStaphylococcal Infections

Identifiers

PMID27442424
PMCPMC4956239
OpenAlexW2492878421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.