ArticleInternational journal of geriatric psychiatry2016
Multimorbidity is associated with anxiety in older adults in the Health and Retirement Study.
Article in International journal of geriatric psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
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Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Patterns of multimorbidity and some psychiatric disorders: A systematic review of the literature.Frontiers in psychology · 2022Pooled it
- Pooled it
- Comorbidities and depressive symptoms among older adults with asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022Trial
- Anxiety: An overlooked confounder in the characterisation of chronic stress-related conditions?PloS one · 2020Trial
- Putative Antianxiety Property of Oral Enalapril Formulation in Mice: a Preclinical andCNS & neurological disorders drug targets · 2026Article
- Association between depression and cognitive function in middle-aged and older adults: a study based on the health and retirement study.Frontiers in psychology · 2026Article
- Association between anxiety and sleep disorders in older adults: evidence from the 2020 health and retirement study.Frontiers in psychology · 2026Article
- Muscle strength and the risk of Multimorbidity in Middle-aged and older Chinese adults: A prospective cohort study.Aging clinical and experimental research · 2025Article
- Review
- Multimorbidity Patterns and Depression: Bridging Epidemiological Associations with Predictive Analytics for Risk Stratification.Healthcare (Basel, Switzerland) · 2025Article
- Multimorbidity and its association with mental health in an adult population of Peru.Revista peruana de medicina experimental y salud publica · 2025Article
- Social Vulnerability and Mental Health Among People with HIV and Substance Use: The Role of Race.AIDS and behavior · 2024Article
- Effects of falls on self-rated health and anxiety in Chinese older persons with chronic multimorbidity : moderating role of psychological resilience.BMC geriatrics · 2024Article
- Understanding the Role of Technology Anxiety in the Adoption of Digital Health Technologies (DHTs) by Older Adults with Chronic Diseases in Shanghai: An Extension of the Unified Theory of Acceptance and Use of Technology (UTAUT) Model.Healthcare (Basel, Switzerland) · 2024Article
- Plant-Based Diets and Risk of Multimorbidity: The Health and Retirement Study.The Journal of nutrition · 2024Article
- Longitudinal Associations Between Multimorbidities and Patient-Reported Quality of Life.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Predictive variables of depressive symptoms and anxiety in older adults from primary care: a cross-sectional observational study.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2024Observational
- Psychometric validation of the Hospital Anxiety and Depression Scale (HADS) in community-dwelling older adults.BMC psychiatry · 2023Article
- Psycho-social and health predictors of loneliness in older primary care patients and mediating mechanisms linking comorbidities and loneliness.BMC geriatrics · 2023Article
- Multimorbidity and complex multimorbidity in Brazilians with severe obesity.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
Abstract
objectivesThe present study determined whether the number of medical conditions was associated with increased occurrence of anxiety and whether triads of medical conditions were associated with anxiety in a nationally representative sample of older Americans. We determined whether multimorbidity findings were unique to anxiety as compared with depressive symptoms.
methodsA sample of 4219 participants (65 years or older) completed anxiety and depression measures in the Health and Retirement Study 2006 wave. The logistic regression models' outcome was elevated anxiety (≥12 on five-item Beck Anxiety Inventory) or depressive symptoms (≥12 on eight-item Center for Epidemiological Studies Depression Scale). The predictor variable was a tally of seven self-report of doctor-diagnosed conditions: arthritis, cancer, diabetes, heart conditions, high blood pressure, lung disease, and stroke. Analyses were adjusted for age, gender, and depressive or anxiety symptoms. Associations among elevated anxiety or depressive symptoms and 35 triads of medical conditions were examined using Bonferroni corrected chi-square analyses.
resultsThree or more medical conditions conferred a 2.30-fold increase in elevated anxiety (95% confidence interval: 1.44-4.01). Twenty triads were associated with elevated anxiety as compared with 13 associated with depressive symptoms. Six of seven medical conditions, with the exception being stroke, were present in the majority of triads.
conclusionNumber of medical conditions and specific conditions are associated with increased occurrence of elevated anxiety. Compared with elevated depressive symptoms, anxiety is associated with greater multimorbidity. As anxiety and depression cause significant morbidity, it may be beneficial to consider these mental health symptoms when evaluating older adults with multimorbidity. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.
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