Evidence map›Paper›PMID 27441302›Full record

Trial reportPapillomavirus research (Amsterdam, Netherlands)2016

Healthcare providers' beliefs and attitudes regarding risk compensation following HPV vaccination.

Monica L Kasting, Shannon Wilson, Brian E Dixon, Stephen M Downs, Amit Kulkarni, Gregory D Zimet

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Papillomavirus research (Amsterdam, Netherlands), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Give PrEP a chance: moving on from the "risk compensation" concept.Journal of the International AIDS Society · 2019
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Monica L KastingIndiana University Fairbanks School of Public Health, Department of Epidemiology, 1050 Wishard Blvd, RG5, Indianapolis, IN 46202, USA.
Shannon WilsonIndiana University School of Medicine, Department of Pediatrics, 410 W 10 Street Suite 1001, Indianapolis, IN 46202, USA.
Brian E DixonIndiana University Fairbanks School of Public Health, Department of Epidemiology, 1050 Wishard Blvd, RG5, Indianapolis, IN 46202, USA; Regenstrief Institute, Inc., Center for Biomedical Informatics, 1101 W. 10th St., Indianapolis, IN 46202, USA; Center for Health Information and Communication, Department of Veterans Affairs, Veterans Health Administration, Health Services Research and Development Service CIN 13-416, 1481 W. 10th St, 11H, Indianapolis, IN 46202, USA.
Stephen M DownsIndiana University School of Medicine, Department of Pediatrics, 410 W 10 Street Suite 1001, Indianapolis, IN 46202, USA; Regenstrief Institute, Inc., Center for Biomedical Informatics, 1101 W. 10th St., Indianapolis, IN 46202, USA.
Amit KulkarniMerck & Co., 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.
Gregory D ZimetIndiana University School of Medicine, Department of Pediatrics, 410 W 10 Street Suite 1001, Indianapolis, IN 46202, USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of MedicineMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Training in Research for Behavioral Oncology and Cancer Control ProgramR25CA117865 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2006 to 2015
$4.1M
Interdisciplinary Training in Cancer Prevention and ControlT32CA117865 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI Victoria Lee Champion, Catherine E Mosher · 2016 to 2026
$2.4M
NCATS NIH HHS UL1 TR001108NCI NIH HHS R25 CA117865NCI NIH HHS T32 CA117865
6 · The paper itself

Abstract

backgroundProvider recommendation is a significant predictor of HPV vaccine uptake. Prior research suggests that concerns regarding risk compensation could cause some providers to hesitate recommending the HPV vaccine.

methodsDuring 15-30 minute semi-structured interviews in early 2015, 22 U.S. pediatric providers were asked about their beliefs regarding sexual risk compensation and cervical cancer screening following HPV vaccination. Providers were asked if these beliefs result in reservations recommending the vaccine. Interviews were audio-recorded, transcribed, and analyzed using inductive content analysis.

resultsNone of the providers believed the HPV vaccine would result in risky sexual behavior. Half indicated it was better to start vaccination early, before sexual activity was a worry. Others noted that patients' risky behavior decisions happen independently of vaccination. When providers were asked if they were concerned about decreased cervical cancer screening, half said they did not know and some stated they had never thought about it before. The main themes addressed were the significant time lapse between vaccination and screening and that women tend to get over-screened as opposed to under-screened.

conclusionProviders were generally in favor of HPV vaccination and do not perceive risk compensation as a barrier to HPV recommendation.

Indexed as

Health Knowledge, Attitudes, PracticeUnsafe SexChildEarly Detection of CancerFemaleHealth PersonnelHumansMalePapillomavirus InfectionsPapillomavirus VaccinesPatient Acceptance of Health CarePediatriciansRisk AssessmentRisk FactorsRisk-TakingSexual BehaviorPapillomavirus Vaccinesbehaviorcervical cancer screeninghealthcare providerHPV vaccinationrisk compensation

Identifiers

PMID27441302
PMCPMC4946644
OpenAlexW2414885390

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.