ArticleHeliyon2016
Threatening faces induce fear circuitry hypersynchrony in soldiers with post-traumatic stress disorder.
Article in Heliyon, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- The impact of intimate partner violence on facial emotion recognition among Korean baby boomers.European journal of psychotraumatology · 2025Article
- Article
- Structural equation modeling of treatment-related changes in neural connectivity for youth with PTSD.Journal of affective disorders · 2023Article
- Preliminary Observations of Resting-State Magnetoencephalography in Nonmedicated Children with Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2022Article
- Classification of posttraumatic stress disorder and related outcomes in women veterans using magnetoencephalography.Experimental brain research · 2022Article
- The effect of stress and reward on encoding future fear memories.Behavioural brain research · 2022Review
- Spatial and spectral trajectories in typical neurodevelopment from childhood to middle age.Network neuroscience (Cambridge, Mass.) · 2019Article
- Angry and Fearful Face Conflict Effects in Post-traumatic Stress Disorder.Frontiers in psychology · 2019Article
- Separable Effects of Childhood Maltreatment and Adult Adaptive Functioning on Amygdala Connectivity During Emotion Processing.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Veterans with PTSD demonstrate amygdala hyperactivity while viewing threatening faces: A MEG study.Biological psychology · 2018Article
- Post-traumatic stress disorder and chronic hyperconnectivity in emotional processing.NeuroImage. Clinical · 2018Article
- Default Mode Network Oscillatory Coupling Is Increased Following Concussion.Frontiers in neurology · 2018Article
- Paradoxical Prefrontal-Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPost-traumatic stress disorder (PTSD) is associated with atypical responses to emotional face stimuli with preferential processing given to threat-related facial expressions via hyperactive amygdalae disengaged from medial prefrontal modulation.
methodWe examined implicit emotional face perception in soldiers with (n = 20) and without (n = 25) PTSD using magnetoencephalography to define spatiotemporal network interactions, and a subsequent region-of-interest analysis to characterize the network role of the right amygdala and medial prefrontal cortex in threatening face perception.
resultsContrasts of network interactions revealed the PTSD group were hyperconnected compared to controls in the phase-locking response in the 2-24 Hz range for angry faces, but not for happy faces when contrasting groups. Hyperconnectivity in PTSD was greatest in the posterior cingulate, right ventromedial prefrontal cortex, right parietal regions and the right temporal pole, as well as the right amygdala. Graph measures of right amygdala and medial prefrontal connectivity revealed increases in node strength and clustering in PTSD, but not inter-node connectivity. Additionally, these measures were found to correlate with anxiety and depression.
conclusionsIn line with prior studies, amygdala hyperconnectivity was observed in PTSD in relation to threatening faces, but the medial prefrontal cortex also displayed enhanced connectivity in our network-based approach. Overall, these results support preferential neurophysiological encoding of threat-related facial expressions in those with PTSD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.