ArticleTremor and other hyperkinetic movements (New York, N.Y.)2016
Clinical Outcome and Characterization of Local Field Potentials in Holmes Tremor Treated with Pallidal Deep Brain Stimulation.
Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Deep brain stimulation in posterior subthalamic area for Holmes tremor: Case reports with review of the literature.Frontiers in neurology · 2023Article
- Deep Brain Stimulation for Cockayne Syndrome-Associated Movement Disorder.Journal of movement disorders · 2022Article
- Evolving Concepts in Our Understanding and Treatment of Holmes Tremor, Over 100 Years in the Making.Tremor and other hyperkinetic movements (New York, N.Y.) · 2022Review
- Deep Brain Stimulation for Holmes Tremors and Literature Review.Annals of Indian Academy of NeurologyArticle
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
backgroundHolmes tremor (HT) is an irregular, low-frequency rest tremor associated with prominent action and postural tremors. Currently, the most effective stereotactic target and neurophysiologic characterization of HT, specifically local field potentials (LFPs) are uncertain. We present the outcome, intraoperative neurophysiologic analysis with characterization of LFPs in a patient managed with left globus pallidus interna deep brain stimulation (Gpi DBS). CASE REPORT: A 24-year-old male underwent left Gpi DBS for medically refractory HT. LFPs demonstrated highest powers in the delta range in Gpi. At the 6-month follow-up, a 90% reduction in tremor was observed. DISCUSSION: Pallidal DBS should be considered as an alternative target for management of refractory HT. LFP demonstrated neuronal activity associated with higher power in the delta region, similarly seen in patients with generalized dystonia.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.