ArticleEthnicity & disease2016
Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage.
Article in Ethnicity & disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Relationship between platelet distribution width and non-dipping pattern in children with essential hypertension.BMC pediatrics · 2025Article
- Heart rate deceleration and acceleration capacities associated with circadian rhythm of blood pressure in essential hypertension.BMC cardiovascular disorders · 2024Article
- Review
- Concurrent Aerobic Plus Resistance Training Elicits Different Effects on Short-Term Blood Pressure Variability of Hypertensive Patients in Relation to Their Nocturnal Blood Pressure Pattern.Medicina (Kaunas, Lithuania) · 2022Article
- Comparing the associations of clinic vs. ambulatory blood pressure with subclinical organ damage in young healthy adults: the African-PREDICT study.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Elevated Ambulatory Blood Pressure Measurements are Associated with a Progressive Form of Fabry Disease.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Sustained high blood pressure and 24-h ambulatory blood pressure monitoring in Tanzanian adolescents.Scientific reports · 2021Article
- Normotensive non-dipping blood pressure profile does not predict the risk of chronic kidney disease progression.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- The additive effects of OSA and nondipping status on early markers of subclinical atherosclerosis in normotensive patients: a cross-sectional study.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Circadian clock-mediated regulation of blood pressure.Free radical biology & medicine · 2018Review
- Associations of Blood Pressure Dipping Patterns With Left Ventricular Mass and Left Ventricular Hypertrophy in Blacks: The Jackson Heart Study.Journal of the American Heart Association · 2017Article
- Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure.Nutrients · 2016Review
- Health Inequities in Hypertension and Related Organ Damage.Ethnicity & disease · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeA non-dipping pattern of nocturnal blood pressure in hypertensive patients is an established predictor of cardiovascular risk, especially in Blacks. However, data on non-dipping normotensives and cardiovascular risk in this population is sparse. In this study, we aim to determine if a non-dipping profile in a cohort of Black normotensives is associated with cardiac target organ damage.
methodsWe studied ambulatory blood pressure patterns in 43 normotensive Black patients of Caribbean origin and classified their profiles as dippers (DP) and non-dippers (NDP) based on their nocturnal blood pressure profiles. Cardiac target organ damage was estimated from 2-D echocardiogram.
resultsThe mean age of the cohort was 52 years. Both groups were similar with respect to baseline age, sex, weight, height, body mass index and daytime ambulatory BP. There was a statistically significant difference in nocturnal blood pressure between DP and NDP groups (112 ± 7/64 ± 2 mm Hg vs 117 ± 3/69 ± 2 mm Hg, P=.004). The NDP cohort showed evidence of cardiovascular target damage on echocardiography with a significantly increased relative wall thickness (.35 ± .07 cm vs .42 ± .05 cm, P=.001), left ventricular mass index (95 ± 14 vs 105 ± 14 g/m(2), P=.018) and left atrial volume index (26 ± 3.5 vs. 30 ± 3.4, P=.001). Left ventricular geometry in the non-dippers also showed increased concentric remodeling, concentric and eccentric hypertrophy.
conclusionsOur study demonstrates that nocturnal non-dipping of blood pressure in normotensive Blacks of Caribbean origin may be associated with cardiovascular end organ damage thereby providing new surveillance and therapeutic targets.
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