Evidence map›Paper›PMID 27440848›Full record

ArticleBMJ case reports2016

Unusual presentation of disseminated Nocardia abscessus infection in a patient with AIDS.

Jacqueline Sherbuk, Danielle Saly, Lydia Barakat, Onyema Ogbuagu

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Unusual presentation ofAccess microbiology · 2022
    Article
  2. Article
  3. DisseminatedOpen forum infectious diseases · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacqueline SherbukYale-New Haven Hospital, New Haven, Connecticut, USA.
Danielle SalyYale-New Haven Hospital, New Haven, Connecticut, USA.
Lydia BarakatSection of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Onyema OgbuaguSection of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Yale New Haven Hospital · USYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 40-year-old man with AIDS presented with symptoms of a chronic cough, subacute headache, generalised weakness with falls, urinary and faecal incontinence, and acute onset subcutaneous nodules. A chest CT scan showed multiple cavitary and nodular pulmonary infiltrates. MRI of his brain and spinal cord revealed innumerable ring-enhancing lesions. Pathological examination of the purulent material obtained from his subcutaneous lesions, as well as transbronchial tissue specimens obtained by biopsy, revealed beaded and branching Gram-positive rods, subsequently identified by 16S RNA sequencing to be Nocardia abscessus species. We observed an excellent therapeutic response to a combination antimicrobial therapy with resolution of the subcutaneous, pulmonary and central nervous system (CNS) lesions. Infections caused by N. abscessus are rare and typically occur in immunocompromised patients. In this article, we will review the presentation, diagnosis and treatment of N. abscessus infection.

Indexed as

AbscessAcquired Immunodeficiency SyndromeAdultAnti-Infective AgentsBiopsyBrainDiagnosis, DifferentialHumansImmunocompromised HostLungMagnetic Resonance ImagingMaleNocardia InfectionsTomography, X-Ray ComputedAnti-Infective Agents

Identifiers

PMID27440848
PMCPMC4964189
OpenAlexW2479624070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.