Evidence map›Paper›PMID 27440776›Full record

ArticleAmerican journal of physiology. Renal physiology2017

(Pro)Renin receptor regulates potassium homeostasis through a local mechanism.

Chuanming Xu, Aihua Lu, Hong Wang, Hui Fang, Li Zhou, Peng Sun, Tianxin Yang

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Collecting duct renin regulates potassium homeostasis in mice.Acta physiologica (Oxford, England) · 2023
    Article
  4. Article
  5. Soluble (Pro)Renin Receptor as a Negative Regulator of NCC (NaHypertension (Dallas, Tex. : 1979) · 2021
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Role of (pro)renin receptor in albumin overload-induced nephropathy in rats.American journal of physiology. Renal physiology · 2018
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Chuanming XuInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China.
Aihua LuInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China.
Hong WangInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China.
Hui FangInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China.
Li ZhouInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China.
Peng SunAnesthesiology, Sun Yat-sen University Cancer Center, Guangzhou, China; and.
Tianxin YangInstitute of Hypertension, Sun Yat-sen University School of Medicine, Guangzhou, China; Tianxin.Yang@hsc.utah.edu.
Sun Yat-sen University · CN

Funding

Control of collecting duct function by lipid-derived factors in obesityR01DK094956 · NIDDK · UNIVERSITY OF UTAH · PI YANG, TIANXIN · 2013 to 2017
$1.6M
NIDDK NIH HHS R01 DK094956
6 · The paper itself

Abstract

(Pro)renin receptor (PRR) is highly expressed in the distal nephron, but it has an unclear functional implication. The present study was conducted to explore a potential role of renal PRR during high K

Indexed as

Potassium, DietaryRenin-Angiotensin SystemAdrenalectomyAldosteroneAnimalsCytochrome P-450 CYP11B2Disease Models, AnimalEpithelial Sodium ChannelsHomeostasisHyperkalemiaKidneyLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMaleMineralocorticoid Receptor AntagonistsPeptide FragmentsPotassium Channels, Inwardly RectifyingAldosteroneATP6AP2 protein, ratCytochrome P-450 CYP11B2Epithelial Sodium ChannelsKcnj1 protein, ratKcnma1 protein, ratLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMineralocorticoid Receptor AntagonistsPeptide FragmentsPotassium Channels, Inwardly RectifyingPotassium, DietaryPRO20 peptideProrenin ReceptorProton-Translocating ATPasesReceptors, Cell SurfaceReninScnn1b protein, ratSlc12a3 protein, ratSolute Carrier Family 12, Member 3SpironolactoneVacuolar Proton-Translocating ATPasesaldosteroneCYP11B2kidneyNa+-Cl− cotransporterpotassium(Pro)renin receptor

Identifiers

PMID27440776
PMCPMC5625102
OpenAlexW2485882945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.