Evidence map›Paper›PMID 27440242›Full record

ArticleJournal of neurophysiology2016

Fatigue diminishes motoneuronal excitability during cycling exercise.

Joshua C Weavil, Simranjit K Sidhu, Tyler S Mangum, Russell S Richardson, Markus Amann

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02209610 (Premature Fatigue in Veterans With Heart Failure), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02209610 early_phase1completednot on this map

Premature Fatigue in Veterans With Heart Failure: Neuronal Influences

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2015 to 2017Enrolled32ConditionsHeart FailureArmsElectrical and Magnetic Nerve Stimulators, Intrathecal Fentanyl
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  10. Electrically induced quadriceps fatigue in the contralateral leg impairs ipsilateral knee extensors performance.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
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  19. Group III/IV locomotor muscle afferents alter motor cortical and corticospinal excitability and promote central fatigue during cycling exercise.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2017
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joshua C WeavilDepartment of Exercise & Sport Science, University of Utah, Salt Lake City, Utah.
Simranjit K SidhuDepartment of Internal Medicine, University of Utah, Salt Lake City, Utah; Discipline of Physiology, University of Adelaide, Australia; and.
Tyler S MangumDepartment of Exercise & Sport Science, University of Utah, Salt Lake City, Utah.
Russell S RichardsonDepartment of Exercise & Sport Science, University of Utah, Salt Lake City, Utah; Department of Internal Medicine, University of Utah, Salt Lake City, Utah; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah.
Markus AmannDepartment of Exercise & Sport Science, University of Utah, Salt Lake City, Utah; Department of Internal Medicine, University of Utah, Salt Lake City, Utah; Geriatric Research, Education, and Clinical Center, George E. Whalen Veterans Affairs Medical Center, Salt Lake City, Utah markus.amann@hsc.utah.edu.
University of Utah · USGeriatric Research Education and Clinical Center · US

Funding

Role of Sensory Neurons in Human Cardiovascular DiseaseR01HL116579 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2021
$3.4M
Premature fatigue in veterans with heart failure: neuronal influencesI21RX001572 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI AMANN, MARKUS · 2015 to 2016
–
NHLBI NIH HHS R01 HL116579RRD VA I21 RX001572
6 · The paper itself

Abstract

Exercise-induced fatigue influences the excitability of the motor pathway during single-joint isometric contractions. This study sought to investigate the influence of fatigue on corticospinal excitability during cycling exercise. Eight men performed fatiguing constant-load (80% W

Indexed as

AdultBicyclingElectric StimulationElectromyographyEvoked Potentials, MotorExerciseFemoral NerveHumansLegMaleMotor NeuronsMuscle FatigueMuscle, SkeletalPyramidal TractsTranscranial Magnetic Stimulationcorticospinal pathwayelectromyographymotor cortexmotor neuron

Identifiers

PMID27440242
PMCPMC5144707
OpenAlexW2483714862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.