ArticleRevista panamericana de salud publica = Pan American journal of public health2015
SPIRIT 2013 Statement: defining standard protocol items for clinical trials.
Article in Revista panamericana de salud publica = Pan American journal of public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 230 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
230 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Physical exercise and major depressive disorder in adults: systematic review and meta-analysis.Scientific reports · 2023Pooled it
- Treatment after traumatic shoulder dislocation: a systematic review with a network meta-analysis.British journal of sports medicine · 2018Pooled it
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- Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.Nature medicine · 2024Trial
- High-intensity resistance training improves quality of life, muscle endurance and strength in patients with myositis: a randomised controlled trial.Rheumatology international · 2024Trial
- Effects of the WHO Labour Care Guide on cesarean section in India: a pragmatic, stepped-wedge, cluster-randomized pilot trial.Nature medicine · 2024Trial
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- A novel brief treatment for methamphetamine use disorders in South Africa: a randomised feasibility trial.Addiction science & clinical practice · 2021Trial
- Comparative Cognitive Effects of Choreographed Exercise and Multimodal Physical Therapy in Older Adults with Amnestic Mild Cognitive Impairment: Randomized Clinical Trial.Journal of Alzheimer's disease : JAD · 2020Trial
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- Exoskeleton-assisted physiotherapy in school and outpatient contexts for minimally ambulant children with cerebral palsy.Developmental medicine and child neurology · 2026Article
- Association Between Dynamic Changes in the Sling-Pubis Gap and Urinary Symptoms After Tension-Free Vaginal Tape Surgery: Protocol for a Prospective Observational Pilot Study.JMIR research protocols · 2026Article
- Promoting psychological resilience during the perinatal period with a digital tool (the HealthyMoms4MentalHealth-app): a study protocol for a randomised controlled trial in Sweden.BMC public health · 2026Article
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- Contemporary practices in scoping review protocol registration: a meta-research analysis of high-impact health journals (2024-2025).BMC medical research methodology · 2026Article
- Article
170 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
Abstract
The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol. The 33-item SPIRIT checklist applies to protocols for all clinical trials and focuses on content rather than format. The checklist recommends a full description of what is planned; it does not prescribe how to design or conduct a trial. By providing guidance for key content, the SPIRIT recommendations aim to facilitate the drafting of high-quality protocols. Adherence to SPIRIT would also enhance the transparency and completeness of trial protocols for the benefit of investigators, trial participants, patients, sponsors, funders, research ethics committees or institutional review boards, peer reviewers, journals, trial registries, policymakers, regulators, and other key stakeholders.
Indexed as
Identifiers
27440100PMC5114122What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.