ArticleThe American journal of clinical nutrition2016
Early exclusive breastfeeding is associated with longer telomeres in Latino preschool children.
Article in The American journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Leukocyte telomere length and obesity in children and adolescents: A systematic review and meta-analysis.Frontiers in genetics · 2022Pooled it
- Effectiveness of targeting fathers for breastfeeding promotion: systematic review and meta-analysis.BMC public health · 2018Pooled it
- Association between telomere length and atopic dermatitis among school-age children.Clinical and translational allergy · 2025Article
- Association Between Adverse Early Life Factors and Telomere Length in Middle and Late Life.Innovation in aging · 2024Article
- The interaction of socioeconomic stress and race on telomere length in children: A systematic review and meta-analysis.SSM - population health · 2023Article
- Obesity at Age 6 Months Is Associated with Shorter Preschool Leukocyte Telomere Length Independent of Parental Telomere Length.The Journal of pediatrics · 2021Article
- The double burden of malnutrition: aetiological pathways and consequences for health.Lancet (London, England) · 2020Review
- The association between intimate partner violence against women and newborn telomere length.Translational psychiatry · 2019Article
- Shorter preschool, leukocyte telomere length is associated with obesity at age 9 in Latino children.Clinical obesity · 2018Article
- Increased Cellular Aging by 3 Years of Age in Latino, Preschool Children Who Consume More Sugar-Sweetened Beverages: A Pilot Study.Childhood obesity (Print) · 2018Article
- The fetal programming of telomere biology hypothesis: an update.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- The paternal age at conception effect on offspring telomere length: mechanistic, comparative and adaptive perspectives.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Leukocyte Telomere Length at Birth and During the Early Life of Children Exposed to but Uninfected With HIV After In Utero Exposure to Antiretrovirals.The Journal of infectious diseases · 2018Article
- Article
- No evidence for parental age effects on offspring leukocyte telomere length in free-living Soay sheep.Scientific reports · 2017Article
- Early life infection, but not breastfeeding, predicts adult blood telomere lengths in the Philippines.American journal of human biology : the official journal of the Human Biology Council · 2017Article
- Paternal and grandpaternal ages at conception and descendant telomere lengths in chimpanzees and humans.American journal of physical anthropology · 2017Article
- Early life adiposity and telomere length across the life course: a systematic review and meta-analysis.Wellcome open research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 3 countries.
Funding
Abstract
backgroundTelomere length (TL) is a marker of cellular aging, with the majority of lifetime attrition occurring during the first 4 y. Little is known about risk factors for telomere shortening in childhood.
objectiveWe evaluated the relation between early life feeding variables and preschool TL.
designWe assessed the relation between dietary, feeding, and weight-associated risk factors measured from birth and TL from blood samples taken at 4 y of age (n = 108) and 5 y of age (n = 92) in a cohort of urban, Latino children (n = 121 individual children). Feeding variables were evaluated in children with repeat measurements (n = 77).
resultsMean TL (in bp) was associated with exclusive breastfeeding at 4-6 wk of age (adjusted coefficient: 353.85; 95% CI: 72.81, 634.89; P = 0.01), maternal TL (adjusted coefficient: 0.32; 95% CI: 0.11, 0.54; P < 0.01), and older paternal age (adjusted coefficient: 33.27; 95% CI: 4.10, 62.44; P = 0.03). The introduction of other foods or drinks in addition to breast-milk or replacement-milk substitutes before 4-6 wk of age was associated with mean TL at 4 and 5 y of age (adjusted coefficient: -457.01; 95% CI: -720.50, -193.51; P < 0.01). Infant obesity at 6 mo of age and soda consumption at 4 y of age mediated the relation in part between exclusive breastfeeding at 4-6 wk of age and mean TL at 4 and 5 y of age. High soda consumption at 3 y of age was associated with an accelerated attrition from 4 to 5 y of age (adjusted coefficient: -515.14; 95% CI: -986.06, -41.22; P = 0.03).
conclusionExclusive breastfeeding at 4-6 wk of age may have long-term effects on child health as evidenced by longer TL at 4 and 5 y of age.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.