Evidence map›Paper›PMID 27439958›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2016

Labial Salivary Glands in Infants: Histochemical Analysis of Cytoskeletal and Antimicrobial Proteins.

Mechthild Stoeckelhuber, Denys J Loeffelbein, Bernhard Olzowy, Christoph Schmitz, Steffen Koerdt, Marco R Kesting

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The Involvement of Alarmins in the Pathogenesis of Sjögren's Syndrome.International journal of molecular sciences · 2022
    Review
  3. Article
  4. Diversity of mucins in labial glands of infants.Histology and histopathology · 2020
    Article
  5. Article
  6. Immunolocalization of Surfactant Proteins SP-A, SP-B, SP-C, and SP-D in Infantile Labial Glands and Mucosa.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2018
    Article
  7. Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mechthild StoeckelhuberDepartment of Oral and Maxillofacial Surgery, Technical University of Munich, Munich, Germany (MS, DJL, SK, MRK)
Denys J LoeffelbeinDepartment of Oral and Maxillofacial Surgery, Technical University of Munich, Munich, Germany (MS, DJL, SK, MRK)
Bernhard OlzowyDepartment of Otorhinolaryngology, Ludwig Maximilians University of Munich, Munich, Germany (BO)
Christoph SchmitzDepartment of Neuroanatomy, Ludwig Maximilians University of Munich, Munich, Germany (CS)
Steffen KoerdtDepartment of Oral and Maxillofacial Surgery, Technical University of Munich, Munich, Germany (MS, DJL, SK, MRK)
Marco R KestingDepartment of Oral and Maxillofacial Surgery, Technical University of Munich, Munich, Germany (MS, DJL, SK, MRK)
Ludwig-Maximilians-Universität München · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human labial glands secrete mucous and serous substances for maintaining oral health. The normal microbial flora of the oral cavity is regulated by the acquired and innate immune systems. The localization and distribution of proteins of the innate immune system were investigated in serous acinar cells and the ductal system by the method of immunohistochemistry. Numerous antimicrobial proteins could be detected in the labial glands: β-defensin-1, -2, -3; lysozyme; lactoferrin; and cathelicidin. Cytoskeletal components such as actin, myosin II, cytokeratins 7 and 19, α- and β-tubulin were predominantly observed in apical cell regions and may be involved in secretory activities.

Indexed as

ActinsAntimicrobial Cationic PeptidesCathelicidinsChild, PreschoolCytoskeletal ProteinsDefensinsFemaleHumansInfantLactoferrinLipMaleMuramidaseSalivary GlandsActinsAntimicrobial Cationic PeptidesCathelicidinsCytoskeletal ProteinsDefensinsLactoferrinMuramidaseantimicrobial proteinscytoskeletonhuman labial glandimmunohistochemistryminor salivary gland

Identifiers

PMID27439958
PMCPMC4971782
OpenAlexW2483782548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.