ArticleAnnals of intensive care2016
Predictors of posttraumatic stress and quality of life in family members of chronically critically ill patients after intensive care.
Article in Annals of intensive care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review.Anaesthesiology intensive therapy · 2023Pooled it
- Effect of an intensive care unit virtual reality intervention on relatives´ mental health distress: a multicenter, randomized controlled trial.Critical care (London, England) · 2025Trial
- Trial
- The Association between Patient Health Status and Surrogate Decision Maker Post-Traumatic Stress Disorder Symptoms in Chronic Critical Illness.Annals of the American Thoracic Society · 2021Trial
- Risk Factors for Post-Traumatic Stress Disorder Symptoms in Surrogate Decision-Makers of Patients with Chronic Critical Illness.Annals of the American Thoracic Society · 2018Trial
- Trial
- Post-traumatic stress disorder, anxiety, and depression in North African intensive care unit survivors: a prospective observational study.Acute and critical care · 2025Article
- Psychological symptoms, quality of life and dyadic relations in family members of intensive care survivors: a multicentre, prospective longitudinal cohort study.Annals of intensive care · 2025Article
- Risk prediction models for post-intensive care syndrome of ICU discharged patients: A systematic review.International journal of nursing sciences · 2025Review
- Article
- The Global Burden of Sepsis and Septic Shock.Epidemiologia (Basel, Switzerland) · 2024Review
- LASSO-Based Machine Learning Algorithm for Prediction of PICS Associated with Sepsis.Infection and drug resistance · 2024Article
- Article
- Article
- The impact of an intensive care unit admission on the health status of relatives of intensive care survivors: A prospective cohort study in primary care.The European journal of general practice · 2022Article
- Minimizing Post-Intensive Care Syndrome to Improve Outcomes for Intensive Care Unit Survivors.Critical care nurse · 2022Article
- Mental health symptoms in family members of COVID-19 ICU survivors 3 and 12 months after ICU admission: a multicentre prospective cohort study.Intensive care medicine · 2022Article
- Psychiatric management of Patients in intensive care units.Indian journal of psychiatry · 2022Article
- Special Characteristics of the Resilience of Russian Families in the Face of Modern Challenges (A Preliminary Study).Psychology in Russia : state of the art · 2022Article
- Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProlonged mechanical ventilation for acute medical conditions increases the risk of chronic critical illness (CCI). Close family members are confronted with the life-threatening condition of the CCI patients and are prone to develop posttraumatic stress disorder affecting their health-related quality of life (HRQL). Main aim of the present study was to investigate patient- and family-related risk factors for posttraumatic stress and decreased HRQL in family members of CCI patients.
methodsIn a cross-sectional design nested within a prospective longitudinal cohort study, posttraumatic stress symptoms and quality of life were assessed in family members of CCI patients (n = 83, aged between 18 and 72 years) up to 6 months after transfer from ICU at acute care hospital to post-acute rehabilitation. Patients admitted a large rehabilitation hospital for ventilator weaning. The Posttraumatic Stress Scale-10 and the Euro-Quality of life-5D-3L were applied in both patients and their family members via telephone interview.
resultsA significant proportion of CCI patients and their family members (14.5 and 15.7 %, respectively) showed clinically relevant scores of posttraumatic stress. Both CCI patients and family members reported poorer HRQL than a normative sample. Factors independently associated with posttraumatic stress in family members were the time following ICU discharge (β = .256, 95 % confidence interval .053-.470) and the patients' diagnosis of PTSD (β = .264, 95 % confidence interval .045-.453). Perceived satisfaction with the relationship turned out to be a protective factor for posttraumatic stress in family members of CCI patients (β = -.231, 95 % confidence interval -.423 to -.015). Regarding HRQL in family members, patients' acute posttraumatic stress at ICU (β = -.290, 95 % confidence interval -.360 to -.088) and their own posttraumatic stress 3 to 6 months post-transfer (β = -.622, 95 % confidence interval -.640 to -.358) turned out to be significant predictors.
conclusionsPosttraumatic stress and HRQL should be routinely assessed in family members of CCI patients at regular intervals starting early at ICU. Preventive family-centered interventions are needed to improve posttraumatic stress and HRQL in both patients and their family members.
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