Evidence map›Paper›PMID 27439650›Full record

ArticleInfluenza and other respiratory viruses2017

Epidemiology and clinical characteristics of respiratory syncytial virus infections among children and adults in Mexico.

Ana E Gamiño-Arroyo, Sarbelio Moreno-Espinosa, Beatriz Llamosas-Gallardo, Ana A Ortiz-Hernández, M Lourdes Guerrero, Arturo Galindo-Fraga, Juan F Galán-Herrera, Francisco J Prado-Galbarro, John H Beigel, Guillermo M Ruiz-Palacios and 2 more

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Systematic review on respiratory syncytial virus epidemiology in adults and the elderly in Latin America.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Pooled it
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Respiratory Infant Mortality Rate by Month of Birth in Mexico.Epidemiologia (Basel, Switzerland) · 2025
    Article
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  17. Review
  18. Review
  19. Respiratory Syncytial Virus Prefusion F Protein Vaccine Is Efficacious in Older Adults With Underlying Medical Conditions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Ana E Gamiño-ArroyoHospital Infantil de México Federico Gómez, Mexico City, Mexico.
Sarbelio Moreno-EspinosaHospital Infantil de México Federico Gómez, Mexico City, Mexico.
Beatriz Llamosas-GallardoInstituto Nacional de Pediatría, Mexico City, Mexico.
Ana A Ortiz-HernándezInstituto Nacional de Pediatría, Mexico City, Mexico.
M Lourdes GuerreroInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Arturo Galindo-FragaInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Juan F Galán-HerreraMexico Emerging Infectious Diseases Clinical Research Network Coordinating Center, Mexico City, Mexico.
Francisco J Prado-GalbarroAgencia de Evaluación de Tecnologías Sanitarias, Instituto de Salud Carlos III, Madrid, Spain.
John H BeigelLeidos Biomedical, Frederick, MD, in support of the National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Guillermo M Ruiz-PalaciosInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Daniel E NoyolaUniversidad Autónoma de San Luis Potosí, San Luis Potosí, Mexico.
Mexico Emerging Infectious Diseases Clinical Research Network (La Red)
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXHospital Infantil de México Federico Gómez · MXInstituto Nacional de Pediatria · MXAutonomous University of San Luis Potosí · MXInstituto de Salud Carlos III · ESLeidos (United States) · USMSD (Mexico) · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory syncytial virus (RSV) is a leading etiological agent of acute respiratory tract infections and hospitalizations in children. However, little information is available regarding RSV infections in Latin American countries, particularly among adult patients.

objectiveTo describe the epidemiology of RSV infection and to analyze the factors associated with severe infections in children and adults in Mexico.

methodsPatients ≥1 month old, who presented with an influenza-like illness (ILI) to six hospitals in Mexico, were eligible for participation in the study. Multiplex reverse-transcriptase polymerase chain reaction identified viral pathogens in nasal swabs from 5629 episodes of ILI. Patients in whom RSV was detected were included in this report.

resultsRespiratory syncytial virus was detected in 399 children and 171 adults. RSV A was detected in 413 cases and RSV B in 163, including six patients who had coinfection with both subtypes; 414 (72.6%) patients required hospital admission, including 96 (16.8%) patients that required admission to the intensive care unit. Coinfection with one or more respiratory pathogens other than RSV was detected in 159 cases. Young age (in children) and older age (in adults) as well as the presence of some underlying conditions were associated with more severe disease.

conclusionsThis study confirms that RSV is an important respiratory pathogen in children in Mexico. In addition, a substantial number of cases in adults were also detected highlighting the relevance of this virus in all ages. It is important to identify subjects at high risk of complications who may benefit from current or future preventive interventions.

Indexed as

Acute DiseaseAdolescentAdultChildChild, PreschoolCoinfectionFemaleHospitalizationHumansInfantInfant, NewbornInfluenza, HumanMaleMexicoMiddle AgedRespiratory Syncytial Virus, Humanacute respiratory tract infectionsbronchiolitisinfluenza-like illnesspneumoniarespiratory syncytial virus

Identifiers

PMID27439650
PMCPMC5155644
OpenAlexW2478792427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.