Evidence map›Paper›PMID 27439593›Full record

Trial reportInternational journal of obesity (2005)2016

Exercise-induced improvements in liver fat and endothelial function are not sustained 12 months following cessation of exercise supervision in nonalcoholic fatty liver disease.

C J A Pugh, V S Sprung, H Jones, P Richardson, F Shojaee-Moradie, A M Umpleby, D J Green, N T Cable, M I Trenell, G J Kemp and 1 more

Open access · bronzeAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in International journal of obesity (2005), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
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  17. Review
  18. Article
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  20. Lifestyle modification in NAFLD/NASH: Facts and figures.JHEP reports : innovation in hepatology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

C J A PughCardiff School of Sport, Cardiff Metropolitan University, Cardiff, UK.
V S SprungDepartment of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
H JonesResearch Institute for Sport & Exercise Science, Liverpool John Moores University, Liverpool, UK.
P RichardsonDepartment of Hepatology, Royal Liverpool University Hospital, Liverpool, UK.
F Shojaee-MoradieDiabetes and Metabolic Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
A M UmplebyDiabetes and Metabolic Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
D J GreenResearch Institute for Sport & Exercise Science, Liverpool John Moores University, Liverpool, UK.
N T CableResearch Institute for Sport & Exercise Science, Liverpool John Moores University, Liverpool, UK.
M I TrenellInstitute of Cellular Medicine, Newcastle University, Newcastle, UK.
G J KempDepartment of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
D J CuthbertsonDepartment of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
University of Liverpool · GBLiverpool John Moores University · GBUniversity of Surrey · GBCardiff Metropolitan University · GBNewcastle University · GB

Funding

Alzheimer's Society 189Department of Health SRF-2011-04-017Medical Research Council G0700718Medical Research Council MR/K006312/1Medical Research Council MR/L016354/1
6 · The paper itself

Abstract

Supervised exercise reduces liver fat and improves endothelial function, a surrogate of cardiovascular disease (CVD) risk, in nonalcoholic fatty liver disease (NAFLD). We hypothesised that after a 16-week supervised exercise program, patients would maintain longer-term improvements in cardiorespiratory fitness, liver fat and endothelial function. Ten NAFLD patients (5/5 males/females, age 51±13 years, body mass index 31±3 kg m

Indexed as

Exercise TherapyAdipose TissueBrachial ArteryEndothelium, VascularFemaleHumansLiverLongitudinal StudiesMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseObesityPatient CompliancePilot ProjectsRecurrenceTreatment Outcome

Identifiers

PMID27439593
OpenAlexW2487947670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.