Evidence map›Paper›PMID 27439592›Full record

ArticleThe British journal of radiology2016

Diagnostic accuracy of a modified subtraction coronary CT angiography method with short breath-holding time: a feasibility study.

Kunihiro Yoshioka, Ryoichi Tanaka, Hidenobu Takagi, Kyouhei Nagata, Takuya Chiba, Kouta Takeda, Takanori Ueda, Tsuyoshi Sugawara, Akinobu Sasaki, Yuta Ueyama and 2 more

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Article in The British journal of radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kunihiro Yoshioka1 Division of Cardiovascular Radiology, Department of Radiology, Iwate Medical University, Morioka, Japan.ORCID http://orcid.org/0000-0002-0100-042X
Ryoichi Tanaka1 Division of Cardiovascular Radiology, Department of Radiology, Iwate Medical University, Morioka, Japan.
Hidenobu Takagi1 Division of Cardiovascular Radiology, Department of Radiology, Iwate Medical University, Morioka, Japan.
Kyouhei Nagata2 Division of Cardiology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Takuya Chiba3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Kouta Takeda3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Takanori Ueda3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Tsuyoshi Sugawara3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Akinobu Sasaki3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Yuta Ueyama3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Kei Kikuchi3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.
Tadashi Sasaki3 Center for Radiological Science, Iwate Medical University Hospital, Morioka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the feasibility and diagnostic accuracy of modified subtraction coronary CT angiography (CCTA) with short breath-holding time in patients who have limited breath-hold capability and severe coronary artery calcification.

methods11 patients with a coronary calcium score >400 underwent CCTA using a modified subtraction protocol. All patients were unable to hold their breath for more than 20 s. Subjective image quality using a four-point scale and the presence of significant (>50%) luminal stenosis were assessed for each calcified or stented segment on both conventional CCTA and modified subtraction CCTA images and compared with invasive coronary angiography (ICA) as the gold standard.

resultsThe mean breath-holding time was 13.0 ± 0.9 s. A total of 35 calcified or stented coronary segments were evaluated. The average image quality was increased from 2.1 ± 0.9 with conventional CCTA to 3.1 ± 0.7 with subtraction CCTA (p < 0.001). The segment-based diagnostic accuracy for detecting significant stenosis according to ICA revealed an area under the receiver-operating characteristic curve of 0.722 for conventional CCTA and 0.892 for subtraction CCTA (p = 0.036).

conclusionModified subtraction CCTA allows the breath-holding time to be shortened to <15 s. As compared with conventional CCTA, modified subtraction CCTA showed improvement in image quality and diagnostic accuracy in patients with limited breath-hold capability and severe calcification. ADVANCES IN KNOWLEDGE: Modified subtraction CCTA can improve the diagnostic accuracy in patients with a high calcium score and patients who are unable to perform long breath-holds.

Indexed as

Angiography, Digital SubtractionBreath HoldingAgedArtifactsComputed Tomography AngiographyCoronary StenosisFeasibility StudiesFemaleHumansMalePredictive Value of TestsRadiographic Image Interpretation, Computer-AssistedSensitivity and SpecificityVascular Calcification

Identifiers

PMID27439592
PMCPMC5124815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.