ArticleThe Journal of antimicrobial chemotherapy2016
Transmission of MDR MRSA between primates, their environment and personnel at a United States primate centre.
Article in The Journal of antimicrobial chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Antimicrobial Resistance and Biofilm in Bacteria from Rehabilitated Sapajus libidinosus.EcoHealth · 2026Article
- Clade-specific adaptation and global spread ofmSystems · 2026Article
- Phenotypic and Genotype Patterns of Antimicrobial Resistance in Non-Human Primates: An Overlooked "One Health" Concern.Antibiotics (Basel, Switzerland) · 2025Review
- Recent Developments in the Antimicrobial Potential of Some Nitrogenous Heterocycles and their SAR Studies: A Review.Current medicinal chemistry · 2025Review
- An Epidemiologic Study of Bacterial Culture and Antibiotic Susceptibility Analyses in Captive Macaques and Marmosets at the Wisconsin National Primate Research Center.Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Evidence of potentialMicrobial genomics · 2023Article
- Pet animals as reservoirs for spreading methicillin-resistantJournal of advanced veterinary and animal research · 2023Article
- Identification of Vancomycin Resistance in Methicillin-resistantFrontiers in immunology · 2023Article
- The effectiveness of newly synthesized quaternary ammonium salts differing in chain length and type of counterion against priority human pathogens.Scientific reports · 2022Article
- Sequence Analysis of NovelInternational journal of molecular sciences · 2022Article
- Article
- Performance Evaluation of the IR BiotyperAntibiotics (Basel, Switzerland) · 2022Article
- Description of Staphylococcal Strains from Straw-Coloured Fruit Bat (Frontiers in cellular and infection microbiology · 2022Review
- Association of Primate Veterinarians' Guidelines for the Judicious Use of Antimicrobials.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Methicillin-Resistant and Methicillin-SusceptibleAntibiotics (Basel, Switzerland) · 2021Article
- The Prevalence ofAnimals : an open access journal from MDPI · 2021Article
- Article
- Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Comparative medicine · 2020Article
- Prevalence, risk factors, phenotypic and molecular characteristics for Staphylococcus aureus carriage in community-based drug users in Guangzhou, China.Antimicrobial resistance and infection control · 2020Article
- Review
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8 authors.
Funding
Abstract
objectivesMDR MRSA isolates cultured from primates, their facility and primate personnel from the Washington National Primate Research Center were characterized to determine whether they were epidemiologically related to each other and if they represented common local human-associated MRSA strains.
methodsHuman and primate nasal and composite environmental samples were collected, enriched and selected on medium supplemented with oxacillin and polymyxin B. Isolates were biochemically verified as Staphylococcus aureus and screened for the mecA gene. Selected isolates were characterized using SCCmec typing, MLST and WGS.
resultsNasal cultures were performed on 596 primates and 105 (17.6%) were MRSA positive. Two of 79 (2.5%) personnel and two of 56 (3.6%) composite primate environmental facility samples were MRSA positive. Three MRSA isolates from primates, one MRSA from personnel, two environmental MRSA and one primate MSSA were ST188 and were the same strain type by conventional typing methods. ST188 isolates were related to a 2007 ST188 human isolate from Hong Kong. Both MRSA isolates from out-of-state primates had a novel MLST type, ST3268, and an unrelated group. All isolates carried ≥1 other antibiotic resistance gene(s), including tet(38), the only tet gene identified.
conclusionsST188 is very rare in North America and has almost exclusively been identified in people from Pan-Asia, while ST3268 is a newly reported MRSA type. The data suggest that the primate MDR MRSA was unlikely to come from primate centre employees. Captive primates are likely to be an unappreciated source of MRSA.
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