Evidence map›Paper›PMID 27439507›Full record

ArticleBMC neurology2016

Laboratory tests as short-term correlates of stroke.

Trevor Sughrue, Michael A Swiernik, Yang Huang, James P Brody

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Stroke Risk in Atrial Fibrillation: Beyond the CHACurrent cardiology reports · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Trevor SughrueKaiser Permanente Southern California, San Diego, CA, USA.
Michael A SwiernikKaiser Permanente Southern California, San Diego, CA, USA.
Yang HuangKaiser Permanente Southern California, San Diego, CA, USA.
James P BrodyDepartment of Biomedical Engineering, University of California-Irvine, Irvine, CA, 92697-2715, USA. jpbrody@uci.edu.
Kaiser Permanente · USUniversity of California, Irvine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke.

methodsWe examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke.

resultsWe identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers.

conclusionSeveral dozen laboratory tests are effective short-term correlates of stroke.

Indexed as

AdolescentAdultAgedAged, 80 and overBlood Cell CountBlood Chemical AnalysisCaliforniaCholesterolCholesterol, HDLCholesterol, LDLClinical Laboratory TechniquesCohort StudiesElectronic Health RecordsFemaleForecastingHeart RateCholesterolCholesterol, HDLCholesterol, LDL

Identifiers

PMID27439507
PMCPMC4955202
OpenAlexW2475956066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.