ArticleBMC cancer2016
Prognostic value of quality of life score in disease-free survivors of surgically-treated lung cancer.
Article in BMC cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Baseline functioning scales of quality of life (EORTC QLQ-C30) as a predictor of overall survival in patients with lung cancer: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Global quality of life and mortality risk in patients with cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- Body mass index and mortality in lung cancer patients: a systematic review and meta-analysis.European journal of clinical nutrition · 2018Pooled it
- Inspiratory Muscle Training in High-Risk Patients Following Lung Resection May Prevent a Postoperative Decline in Physical Activity Level.Integrative cancer therapies · 2018Trial
- Unlocking patient insights: a prospective study on patient reported outcome measures in thoracic surgery.Journal of cardiothoracic surgery · 2026Observational
- Effects of pulmonary rehabilitation in people with lung cancer after lung resection: a systematic review and meta-analysis.Journal of cancer survivorship : research and practice · 2026Review
- Experiences of post-surgery exercise among middle-aged adults with early lung cancer.Open medicine (Warsaw, Poland) · 2026Article
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- Effects of Uncertainty, Appraisal of Uncertainty, and Self-Efficacy on the Quality of Life of Elderly Patients with Lung Cancer Receiving Chemotherapy: Based on Mishel's Theory of Uncertainty.Medicina (Kaunas, Lithuania) · 2023Article
- Prognostic value of patient-reported outcome measures (PROMs) in adults with non-small cell Lung Cancer: a scoping review.BMC cancer · 2022Article
- Evaluation of a Smart After-Care Program for Patients with Lung Cancer: A Prospective, Single-Arm Pilot Study.Journal of chest surgery · 2022Article
- Lung cancer patients with chronic obstructive pulmonary disease benefit from anti-PD-1/PD-L1 therapy.Frontiers in immunology · 2022Review
- An Update on Survivorship Issues in Lung Cancer Patients.World journal of oncology · 2021Review
- Impact of chronic obstructive pulmonary disease on immune checkpoint inhibitor efficacy in advanced lung cancer and the potential prognostic factors.Translational lung cancer research · 2021Article
- Comparison of Chief Complaints and Patient-Reported Symptoms of Treatment-Naive Lung Cancer Patients Before Surgery.Patient preference and adherence · 2021Article
- The major effects of health-related quality of life on 5-year survival prediction among lung cancer survivors: applications of machine learning.Scientific reports · 2020Article
- The mediating effect of social support on uncertainty in illness and quality of life of female cancer survivors: a cross-sectional study.Health and quality of life outcomes · 2020Article
- Sexual Function, Quality of Life, and Experiences of Women with Ovarian Cancer: A Mixed-Methods Study.Sexual medicine · 2019Article
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Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to evaluate the prognostic value of quality of life (QOL) for predicting survival among disease-free survivors of surgically-treated lung cancer after the completion of cancer treatment.
methodsWe administered the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30), the Quality of Life Questionnaire Lung Cancer Module (QLQ-LC13), Hospital Anxiety and Depression Scale (HADS), and Posttraumatic Growth Inventory (PTGI) to 809 survivors who were surgically-treated for lung cancer at two hospitals from 2001 through 2006. We gathered mortality data by linkage to the National Statistical Office through December 2011. We used Cox proportional hazard models to compute adjusted hazard ratios (aHRs) and 95 % confidence intervals (CIs) to estimate the relationship between QOL and survival.
resultsAnalyses of QOL items adjusted for age, sex, stage, body mass index, and physical activity showed that scores for poor physical functioning, dyspnea, anorexia, diarrhea, cough, personal strength, anxiety, and depression were associated with poor survival. With adjustment for the independent indicators of survival, final multiple proportional hazard regression analyses of QOL show that physical functioning (aHR, 2.39; 95 % CI, 1.13-5.07), dyspnea (aHR, 1.56; 95 % CI, 1.01-2.40), personal strength (aHR, 2.36; 95 % CI, 1.31-4.27), and anxiety (aHR, 2.13; 95 % CI, 1.38-3.30) retained their independent prognostic power of survival.
conclusionThis study suggests that patient-reported QOL outcomes in disease-free survivors of surgically-treated lung cancer after the completion of active treatment has independent prognostic value for long-term survival.
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