ArticleScientific reports2016
Bats: Body mass index, forearm mass index, blood glucose levels and SLC2A2 genes for diabetes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Evolutionary History of theAnimals : an open access journal from MDPI · 2026Article
- Relationship between Hg accumulation and diet in bats from Atlantic forest reserves.Ecotoxicology (London, England) · 2026Article
- Factors shaping sugar metabolism in Neotropical bats: A physiological and ecological perspective.PloS one · 2026Article
- Seasonal Expression of Glucose Transporter 5 (GLUT-5) Protein in the Testes of Roundleaf Bats in Thailand.Animals : an open access journal from MDPI · 2025Article
- The relationship between diet, plasma glucose, and cancer prevalence across vertebrates.Nature communications · 2025Article
- Sugar assimilation underlying dietary evolution of Neotropical bats.Nature ecology & evolution · 2024Article
- Glycation resistance and life-history traits: lessons from non-conventional animal models.Biology letters · 2024Review
- The Consumption and Diversity Variation Responses of Agricultural Pests and Their Dietary Niche Differentiation in Insectivorous Bats.Animals : an open access journal from MDPI · 2024Article
- Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas.Nature communications · 2024Article
- Increased urinary creatinine during hibernation and day roosting in the Eastern bent-winged bat (Miniopterus fuliginosus) in Korea.Communications biology · 2024Article
- Viral maintenance and excretion dynamics of coronaviruses within an Egyptian rousette fruit bat maternal colony: considerations for spillover.Scientific reports · 2023Article
- Sex differences in postprandial blood glucose and body surface temperature are contingent on flight in the fruit bat,Biology open · 2021Article
- Article
- Identification of Differentially Expressed Genes under the Regulation of Transcription Factors in Osteosarcoma.Pathology oncology research : POR · 2019Article
- Table for five, please: Dietary partitioning in boreal bats.Ecology and evolution · 2018Article
- Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point.Cell metabolism · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats have an unusually large volume of endocrine tissue, with a large population of beta cells, and an elevated sensitivity to glucose and insulin. This makes them excellent animal models for studying diabetes mellitus. We evaluated bats as models for diabetes in terms of lifestyle and genetic factors. For lifestyle factors, we generated data sets of 149 body mass index (BMI) and 860 forearm mass index (FMI) measurements for different species of bats. Both showed negative inter-species correlations with blood glucose levels in sixteen bats examined. The negative inter-species correlations may reflect adaptation of a small insectivorous ancestor to a larger frugivore. We identified an 11 bp deletion in the proximal promoter of SLC2A2 that we predicted would disrupt binding sites for the transcription repressor ZNF354C. In frugivorous bats this could explain the relatively high expression of this gene, resulting in a better capacity to absorb glucose and decrease blood glucose levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.