Evidence map›Paper›PMID 27439020›Full record

ArticleEmerging infectious diseases2016

Toward Developing a Preventive MERS-CoV Vaccine-Report from a Workshop Organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14-15, 2015.

Jean-Louis Excler, Christopher J Delvecchio, Ryan E Wiley, Marni Williams, In-Kyu Yoon, Kayvon Modjarrad, Mohamed Boujelal, Vasee S Moorthy, Ahmad Salah Hersi, Jerome H Kim and 1 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. SARS-CoV-2 reinfection and implications for vaccine development.Human vaccines & immunotherapeutics · 2020
    Review
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  5. Article
  6. Article
  7. Review
  8. Review
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  12. Vaccines for epidemic infections and the role of CEPI.Human vaccines & immunotherapeutics · 2017
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Development of Recombinant Measles Virus-Based Vaccines.Methods in molecular biology (Clifton, N.J.) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jean-Louis Excler
Christopher J Delvecchio
Ryan E Wiley
Marni Williams
In-Kyu Yoon
Kayvon Modjarrad
Mohamed Boujelal
Vasee S Moorthy
Ahmad Salah Hersi
Jerome H Kim
MERS-CoV Vaccine Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle East respiratory syndrome (MERS) remains a serious international public health threat. With the goal of accelerating the development of countermeasures against MERS coronavirus (MERS-CoV), funding agencies, nongovernmental organizations, and researchers across the world assembled in Riyadh, Saudi Arabia, on November 14-15, 2015, to discuss vaccine development challenges. The meeting was spearheaded by the Saudi Ministry of Health and co-organized by the International Vaccine Institute, South Korea. Accelerating the development of a preventive vaccine requires a better understanding of MERS epidemiology, transmission, and pathogenesis in humans and animals. A combination of rodent and nonhuman primate models should be considered in evaluating and developing preventive and therapeutic vaccine candidates. Dromedary camels should be considered for the development of veterinary vaccines. Several vaccine technology platforms targeting the MERS-CoV spike protein were discussed. Mechanisms to maximize investment, provide robust data, and affect public health are urgently needed.

Indexed as

AnimalsAntibodies, ViralBiomedical ResearchCamelusCoronavirus InfectionsHumansInternational CooperationMiddle East Respiratory Syndrome CoronavirusSaudi ArabiaSpike Glycoprotein, CoronavirusViral VaccinesAntibodies, ViralSpike Glycoprotein, CoronavirusViral Vaccinesanimal modelscoronavirusMERS-CoVMiddle East respiratory syndromepreventionSaudi Arabiatherapeutic antibodiesvaccineviruseszoonosis

Identifiers

PMID27439020
PMCPMC4982192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.