Evidence map›Paper›PMID 27438825›Full record

SynthesisInternational journal of molecular sciences2016

Environmental Factors Associated with Altered Gut Microbiota in Children with Eczema: A Systematic Review.

Carmen W H Chan, Rosa S Wong, Patrick T W Law, Cho Lee Wong, Stephen K W Tsui, Winnie P Y Tang, Janet W H Sit

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Allergy, asthma & immunology research · 2022
    Article
  3. Early Life Antimicrobial Exposure: Impact onAntibiotics (Basel, Switzerland) · 2022
    Article
  4. Daily Lifestyle and Inflammatory Skin Diseases.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Circadian Rhythm Shapes the Gut Microbiota Affecting Host Radiosensitivity.International journal of molecular sciences · 2016
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carmen W H ChanNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. whchan@cuhk.edu.hk.
Rosa S WongNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. szemanwg@hotmail.com.
Patrick T W LawNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. patricklaw@cuhk.edu.hk.
Cho Lee WongNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. jojowong@cuhk.edu.hk.
Stephen K W TsuiSchool of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China. kwtsui@cuhk.edi.hk.
Winnie P Y TangNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. winnie.tang@cuhk.edu.hk.
Janet W H SitNethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China. janet.sit@cuhk.edu.hk.
Chinese University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eczema is a common skin condition that impairs children's daily life activities and quality of life. Previous research shows that gut microbiome composition plays an important role in the development of eczema. The present review summarizes evidence on environmental factors related to altered gut microbiota in children with eczema. We searched Medline, PubMed, Embase, and the Cochrane database of Systematic Reviews through October 2015. The search strategy focused on articles published in peer-reviewed, English-language journals with no publication year limit. Only original studies and review articles that reported environmental factors on gut microbiome specific to eczema were included in this review. We selected six studies (total 1990 participants) for full review and identified that the composition of gut microbiota specific to eczema could be influenced by the following environmental factors: length of gestation, mode of delivery, type of feeding, method of treatment, number of older siblings, and other lifestyle factors. There has been inconsistent empirical evidence as to the modulatory effects of gut microbiota on immunological functions in children with eczema. Further research on the environmental-host-microbial interaction is needed to develop a strong base of knowledge for the development and implementation of prevention strategies and policies for eczema.

Indexed as

Gastrointestinal MicrobiomeChildEczemaEnvironmental ExposureGastrointestinal TractHumansallergy developmentchildhood eczemaenvironmental-host-microbial interactiongene-environment interactiongut microbiotaimmune systemmicrobiome diversity

Identifiers

PMID27438825
PMCPMC4964520
OpenAlexW2496853628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.