Evidence map›Paper›PMID 27438724›Full record

ArticleSleep & breathing = Schlaf & Atmung2017

The effect of obstructive sleep apnea syndrome and hypothyroidism to intima-media thickness of carotid artery.

Fulsen Bozkus, Nursel Dikmen, Gülay Güngör, Anıl Samur

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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  6. AN INTERESTING ETIOLOGY OF VENTRICULAR TACHYCARDIA.Acta endocrinologica (Bucharest, Romania : 2005)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Fulsen BozkusDepartment of Chest Diseases, Kahramanmaras Sutcu Imam University, School of Medicine, Kahramanmaraş, Turkey. fulsenbatmaz@gmail.com.
Nursel DikmenDepartment of Chest Diseases, Kahramanmaras Necip Fazıl State Hospital, Kahramanmaraş, Turkey.
Gülay GüngörDepartment of Radiology, Kahramanmaras Necip Fazıl State Hospital, Kahramanmaraş, Turkey.
Anıl SamurDepartment of Biostatistics, Akdeniz University, School of Medicine, Antalya, Turkey.
Kahramanmaraş Sütçü İmam University · TRAkdeniz University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimObstructive sleep apnea syndrome (OSAS) is a common disorder and in subjects with OSAS the prevalence of hypothyroidism is approximately 1.2-11 %. The episodes of hypoxia/reoxygenation associated with the respiratory disturbances observed in subjects with OSAS increases the risk of cardiovascular diseases. Hypothyroidism; primary or subclinical, has several effects on cardiovascular system. In our study, we investigated carotid artery intima-media thickness (IMT) which is an early sign of atherosclerosis, in OSAS subjects with hypothyroidism. MATERIALS AND

methodSubjects who admitted to Kahramanmaras Necip Fazıl City State Hospital Chest Diseases out-patient clinic between May 2014 and January 2016 for snoring and had polysomnographic evaluation at the sleep laboratory were included in this study. Each subject was evaluated for serum thyroid function tests and carotid artery IMT was measured by a Doppler ultrasound.

resultsMean carotid artery IMT values in the isolated OSAS, OSAS plus hypothyroidism, and control groups were 0.67 ± 0.12, 0.8 ± 0.12, and 0.54 ± 0.08 mm, respectively; difference between groups was statistically significant (p < .05). A poXsitive correlation was found between thyroid stimulating hormone levels and IMT (r = 0.426, p = .002), while free T3 levels and IMT were negatively correlated (r = -0.463, p = .001). IMT and apnea-hypopnea index were also positively correlated (r = 0.403, p = .003).

conclusionWe suggest, physicians should be alert for hypothyroidism comorbidity in OSAS, and suspected subjects with OSAS should be screened for hypothyroidism considering the potential cardiovascular complications.

Indexed as

Carotid Intima-Media ThicknessAdultCardiovascular DiseasesComorbidityFemaleHumansHypothyroidismMaleMiddle AgedPolysomnographyRisk FactorsSleep Apnea, ObstructiveUltrasonography, DopplerCarotid arteryHypothyroidismSleep apnea

Identifiers

PMID27438724
OpenAlexW2485427168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.