ArticleAnnals of neurology2016
New diagnostic criteria for neurocysticercosis: Reliability and validity.
Article in Annals of neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 3 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 119 citations in OpenAlex.
- An updated estimate of the proportion of neurocysticercosis among people with epileptic seizures: a systematic review and Bayesian meta-analysis.Infectious diseases of poverty · 2026Pooled it
- Accuracy of immunological tests on serum and urine for diagnosis of Taenia solium neurocysticercosis: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Reliability of Diagnostic Criteria for Neurocysticercosis for Patients with Ventricular Cystic Lesions or Granulomas: A systematic review.The American journal of tropical medicine and hygiene · 2017Pooled it
- Exploring the complex associations over time among albendazole treatment, cyst evolution, and seizure outcomes in neurocysticercosis.Epilepsia · 2019Trial
- Distinguishing neurocysticercosis epilepsy from epilepsy of unknown etiology using a minimal serum mass profiling platform.Experimental parasitology · 2018Trial
- PCR-Confirmed Convexity Subarachnoid Neurocysticercosis with Negative Serology: A Case Report.Pathogens (Basel, Switzerland) · 2026Article
- A Whole-Blood Point-of-Care Test for Highly Specific Serodiagnosis of Human Cysticercosis.Pathogens (Basel, Switzerland) · 2026Article
- Letters to the Editor: Radiological, parasitological, and biological considerations regarding alleged adult Taenia solium brain infection.Journal of neurosurgery. Case lessons · 2026Article
- Occurrence of autochthonous neurocysticercosis in Germany: a case report.BMC infectious diseases · 2026Article
- Comparison of Effectiveness Between Cysticidal and Surgical Treatments in Patients with Intraventricular Neurocysticercosis: A Single-Center Experience.Pathogens (Basel, Switzerland) · 2026Article
- Comparative assessment of immunochromatographic test kits using low-molecular-weight antigens from cyst fluids of two different genotypes of Taenia solium for serodiagnosis of human cysticercosis.Parasite (Paris, France) · 2026Article
- Repair capacity ofFuture microbiology · 2025Article
- Intradural extramedullary cystic lesions: an interesting cauda equina cysticercosis case report and a literature review.BMC neurology · 2024Review
- Development and evaluation of an immunochromatography-based point-of-care test kit for a rapid diagnosis of human cysticercosis.Food and waterborne parasitology · 2023Article
- Correlation between Monocyte Gene Expression and Inflammation on Brain Imaging in Patients with Solitary Cerebral Cysticercus Granuloma.The American journal of tropical medicine and hygiene · 2023Article
- Can sPD-1 and sPD-L1 Plasma Concentrations Predict Treatment Response among Patients with Extraparenchymal Neurocysticercosis?Pathogens (Basel, Switzerland) · 2023Article
- Low responsiveness of peripheral lymphocytes in extraparenchymal neurocysticercosis.PLoS neglected tropical diseases · 2023Article
- Severe Neurocysticercosis in an Immunocompetent Male Without Travel to an Endemic Region: A Case Report.Cureus · 2023Article
- Human Neurocysticercosis: An Overview.Pathogens (Basel, Switzerland) · 2022Review
- Neurocysticercosis in Latin America: Current epidemiological situation based on official statistics from four countries.PLoS neglected tropical diseases · 2022Article
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Authors and funding
13 authors at 11 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe diagnosis of neurocysticercosis (NCC) remains problematic because of the heterogeneity of its clinical, immunological, and imaging characteristics. Our aim was to develop and assess a new set of diagnostic criteria for NCC, which might allow for the accurate detection of, and differentiation between, parenchymal and extraparenchymal disease.
methodsA group of Latin American NCC experts developed by consensus a new set of diagnostic criteria for NCC. A multicenter, retrospective study was then conducted to validate it. The reference standard for diagnosis of active NCC was the disappearance or reduction of cysts after anthelmintic treatment. In total, three pairs of independent neurologists blinded to the diagnosis evaluated 93 cases (with NCC) and 93 controls (without NCC) using the new diagnostic criteria. Mixed-effects logistic regression models were used to estimate sensitivity and specificity.
resultsInter-rater reliability (kappa) of diagnosis among evaluators was 0.60. For diagnosis of NCC versus no NCC, the new criteria had a sensitivity of 93.2% and specificity of 81.4%. For parenchymal NCC, the new criteria had a sensitivity of 89.8% and specificity of 80.7% and for extraparenchymal NCC, the new criteria had a sensitivity of 65.9% and specificity of 94.9%.
interpretationThese criteria have acceptable reliability and validity and could be a new tool for clinicians and researchers. An advantage of the new criteria is that they consider parasite location (ie, parenchymal or extraparenchymal), which is an important factor determining the clinical, immunological, and radiological presentation of the disease, and importantly, its treatment and prognosis. Ann Neurol 2016;80:434-442.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.