Evidence map›Paper›PMID 27437985›Full record

ArticleObesity surgery2017

Effect of Bariatric Surgery-Induced Weight Loss on Platelet Count and Mean Platelet Volume: a 12-Month Follow-Up Study.

Loïc Raoux, David Moszkowicz, Karina Vychnevskaia, Tigran Poghosyan, Alain Beauchet, Sylvain Clauser, Marion Bretault, Sébastien Czernichow, Claire Carette, Jean-Luc Bouillot

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. The hematologic consequences of obesity.European journal of haematology · 2021
    Review
  8. Article
  9. Influence of Cardiometabolic Risk Factors on Platelet Function.International journal of molecular sciences · 2020
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Loïc RaouxDepartment of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, Boulogne-Billancourt, France.
David MoszkowiczDepartment of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, Boulogne-Billancourt, France. david.moszkowicz@aphp.fr.
Karina VychnevskaiaDepartment of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, Boulogne-Billancourt, France.
Tigran PoghosyanDepartment of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, Boulogne-Billancourt, France.
Alain BeauchetDepartment of Biostatistics, Ambroise Paré Hospital, Boulogne-Billancourt, France.
Sylvain ClauserVersailles St-Quentin-en-Yvelines University, 78180, Montigny-Le-Bretonneux, France.
Marion BretaultVersailles St-Quentin-en-Yvelines University, 78180, Montigny-Le-Bretonneux, France.
Sébastien CzernichowVersailles St-Quentin-en-Yvelines University, 78180, Montigny-Le-Bretonneux, France.
Claire CaretteDepartment of Nutrition, Ambroise Paré Hospital, Boulogne-Billancourt, France.
Jean-Luc BouillotDepartment of Digestive, Oncologic and Metabolic Surgery, Ambroise Paré Hospital, Boulogne-Billancourt, France.
Hôpital Ambroise-Paré · FRUniversité de Versailles Saint-Quentin-en-Yvelines · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbdominal obesity is strongly correlated with cardiovascular risk and associated with platelet hyperactivity. This hyperactivity is associated with an increase in mean platelet volume (MPV). Few data are available about changes in platelet counts and MPV in obese patients after bariatric surgery (BS). The purpose of this study was to describe quantitative and qualitative changes in the platelet lineage after BS.

methodsOne hundred twenty-eight consecutive patients were included. The mean age was 43 ± 12 years, 77 % of patients were female, and the mean preoperative BMI was 44 ± 6 kg/m

resultsAt the 12-month follow-up, the reduction in preoperative weight was 29 ± 9 %. We showed a significant decrease in platelet count (245 ± 62 vs. 234 ± 54 G/L; p = 0.0015) found in parallel with a non-significant decrease in MPV (9.27 ± 1.1 vs. 9.22 ± 1.05; p = 0.34). With regard to the intervention type, SG caused a more significant decrease in platelet count than RYGBP (p = 0.02). There was no significant difference in MPV variations between the two groups (p = 0.08).

conclusionsOur results suggest that BS has a positive impact on platelet metabolism, possibly mediated by weight loss. These data need to be confirmed to understand the multifactorial benefits of BS on cardiovascular risk in obese patients.

Indexed as

Bariatric SurgeryMean Platelet VolumeAdultFemaleFollow-Up StudiesHumansMaleMiddle AgedObesity, MorbidPlatelet CountPostoperative PeriodReoperationWeight LossBariatric surgeryCardiovascular riskGastric bypassObesityPlateletsSleeve gastrectomy

Identifiers

PMID27437985
OpenAlexW2482391250

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.