ArticleBioMed research international2016
Heavy Cigarette Smokers in a Chinese Population Display a Compromised Permeability Barrier.
Article in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Clinical Measurement of Transepidermal Water Loss.Advances in wound care · 2026Review
- Impact of nicotine-free and nicotine-rich flavored electronic cigarette refill liquids on primary human melanocyte function.Toxicology reports · 2025Article
- Medwakh smoking induces alterations in salivary proteins and cytokine expression: a clinical exploratory proteomics investigation.Clinical proteomics · 2025Article
- The effect of long-term cigarette smoking on selected skin barrier proteins and lipids.Scientific reports · 2023Article
- Lipidomic Analysis of Hand Skin Surface Lipids Reveals Smoking-Related Skin Changes.Metabolites · 2023Article
- A review of factors influencing sensitive skin: an emphasis on built environment characteristics.Frontiers in public health · 2023Review
- Unbearable transepidermal water loss (TEWL) experimental variability: why?Archives of dermatological research · 2022Review
- Reframing aging in dermatology: The role of the dermatologist in healthy aging.International journal of women's dermatology · 2021Review
- Associations between occupational and environmental exposures and organ involvement in sarcoidosis: a retrospective case-case analysis.Respiratory research · 2021Article
- Histological study on the effect of nicotine on adult male guinea pig thin skin.Anatomy & cell biology · 2017Article
- Skin condition and its relationship to systemic inflammation in chronic obstructive pulmonary disease.International journal of chronic obstructive pulmonary disease · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cigarette smoking is associated with various cutaneous disorders with defective permeability. Yet, whether cigarette smoking influences epidermal permeability barrier function is largely unknown. Here, we measured skin biophysical properties, including permeability barrier homeostasis, stratum corneum (SC) integrity, SC hydration, skin surface pH, and skin melanin/erythema index, in cigarette smokers. A total of 99 male volunteers were enrolled in this study. Smokers were categorized as light-to-moderate (<20 cigarettes/day) or heavy smokers (≥20 cigarettes/day). An MPA5 was used to measure SC hydration and skin melanin/erythema index on the dorsal hand, forehead, and cheek. Basal transepidermal water loss (TEWL) and barrier recovery rates were assessed on the forearm. A Skin-pH-Meter pH900 was used to measure skin surface pH. Our results showed that heavy cigarette smokers exhibited delayed barrier recovery after acute abrogation (1.02% ± 13.06 versus 16.48% ± 6.07), and barrier recovery rates correlated negatively with the number of daily cigarettes consumption (p = 0.0087). Changes in biophysical parameters in cigarette smokers varied with body sites. In conclusion, heavy cigarette smokers display compromised permeability barrier homeostasis, which could contribute, in part, to the increased prevalence of certain cutaneous disorders characterized by defective permeability. Thus, improving epidermal permeability barrier should be considered for heavy cigarette smokers.
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