ReviewPediatric gastroenterology, hepatology & nutrition2016
Updates on the Diagnosis of Helicobacter pylori Infection in Children: What Are the Differences between Adults and Children?
Review in Pediatric gastroenterology, hepatology & nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05861687 (Comparative Recurrence Rate Investigation of Esomeprazole Versus Lansoprazole in Triple-Combination Therapy to Eradicate Helicobacter Pylori Infection Among Pediatrics), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Recurrence Rate Investigation of Esomeprazole Versus Lansoprazole in Triple-Combination Therapy to Eradicate Helicobacter Pylori Infection Among Pediatrics: Multicentre, Randomized, and Controlled Trials
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Social determinants of health andFrontiers in public health · 2025Pooled it
- Temporal trends and correlates of Helicobacter pylori prevalence in children undergoing upper gastrointestinal endoscopy.European journal of pediatrics · 2026Article
- Review
- Article
- Birth cohort and age-specific trends in globalLancet regional health. Americas · 2025Review
- Prevalence, Management, and Outcomes of Non-InvasivePediatric gastroenterology, hepatology & nutrition · 2024Article
- Gastrointestinal contrast-enhanced ultrasonography for diagnosis and treatment of peptic ulcer in children.World journal of gastroenterology · 2024Article
- Pattern of Primary Resistance ofChildren (Basel, Switzerland) · 2023Article
- Moroccan Children With Helicobacter pylori Infection: Demographics, Clinical Features, and Histological Findings.Cureus · 2023Article
- Antibiotic Resistance and Therapeutic Efficacy ofAntibiotics (Basel, Switzerland) · 2023Article
- Article
- Changing prevalence of Helicobacter pylori infection in children and adolescents.Clinical and experimental pediatrics · 2021Article
- Particular Morphological Features in the Diagnosis of PediatricJournal of clinical medicine · 2020Article
- Article
- Article
- Diagnosis ofPediatric gastroenterology, hepatology & nutrition · 2018Review
- Helicobacter pylori Infection in Pediatric Patients: Update on Diagnosis and Eradication Strategies.Paediatric drugs · 2018Review
- When is Helicobacter pylori acquired in populations in developing countries? A birth-cohort study in Bangladeshi children.Gut microbes · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori infection is acquired mainly during childhood and causes various diseases such as gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue (MALT) lymphoma, and iron deficiency anemia. Although H. pylori infection in children differs from adults in many ways, this is often overlooked in clinical practice. Unlike adults, nodular gastritis may be a pathognomonic endoscopic finding of childhood H. pylori infection. Histopathological findings of gastric tissues are also different in children due to predominance of lymphocytes and plasma cells and the formation of gastric MALT. Although endoscopy is recommended for the initial diagnosis of H. pylori infection, several non-invasive diagnostic tests such as the urea breath test (UBT) and the H. pylori stool antigen test (HpSA) are available and well validated even in children. According to recent data, both the (13)C-UBT and HpSA using enzyme-linked immunosorbent assay are reliable non-invasive tests to determine H. pylori status after eradication therapy, although children younger than 6 years are known to have high false positives. When invasive or noninvasive tests are applied to children to detect H. pylori infection, it should be noted that there are differences between children and adults in diagnosing H. pylori infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.