Evidence map›Paper›PMID 27437039›Full record

ArticleApplied clinical informatics2016

Integrating Heterogeneous Biomedical Data for Cancer Research: the CARPEM infrastructure.

Bastien Rance, Vincent Canuel, Hector Countouris, Pierre Laurent-Puig, Anita Burgun

Abstract read
In one paragraph

Article in Applied clinical informatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bastien RanceUniversity Hospital Georges Pompidou, Paris, France; INSERM UMR_S 1138, CRC, Paris, France.
Vincent CanuelUniversity Hospital Georges Pompidou , Paris, France.
Hector CountourisUniversity Hospital Georges Pompidou, Paris, France; INSERM UMR_S 1138, CRC, Paris, France.
Pierre Laurent-PuigUniversity Hospital Georges Pompidou, Paris, France; Université Paris Sorbonne Cité, Inserm UMR-S 1147, Paris, France.
Anita BurgunUniversity Hospital Georges Pompidou, Paris, France; INSERM UMR_S 1138, CRC, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer research involves numerous disciplines. The multiplicity of data sources and their heterogeneous nature render the integration and the exploration of the data more and more complex. Translational research platforms are a promising way to assist scientists in these tasks. In this article, we identify a set of scientific and technical principles needed to build a translational research platform compatible with ethical requirements, data protection and data-integration problems. We describe the solution adopted by the CARPEM cancer research program to design and deploy a platform able to integrate retrospective, prospective, and day-to-day care data. We designed a three-layer architecture composed of a data collection layer, a data integration layer and a data access layer. We leverage a set of open-source resources including i2b2 and tranSMART.

Indexed as

Biomedical ResearchNeoplasmsHumansInformation Storage and RetrievalSoftwareSystems IntegrationTranslational Research, BiomedicalData integrationmedical information systemstranslational medicinetranslational research platform

Identifiers

PMID27437039
PMCPMC4941838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.