Evidence map›Paper›PMID 27436749›Full record

ArticleDrug and alcohol dependence2016

Magnitude and duration of cue-induced craving for marijuana in volunteers with cannabis use disorder.

Leslie H Lundahl, Mark K Greenwald

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Artificial Intelligence Approximates Human Affect Ratings of Cannabis Images.medRxiv : the preprint server for health sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The importance of psychology for shaping legal cannabis regulation.Experimental and clinical psychopharmacology · 2021
    Review
  10. Article
  11. Article
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  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Leslie H LundahlDepartment of Psychiatry and Behavioral Neurosciences, School of Medicine,Wayne State University, Detroit, MI 48201, USA. Electronic address: llundahl@med.wayne.edu.
Mark K GreenwaldDepartment of Psychiatry and Behavioral Neurosciences, School of Medicine,Wayne State University, Detroit, MI 48201, USA; Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Eugene Applebaum College of Pharmacy and Health Sciences · USWayne State University · US

Funding

Cue Reactivity Model/Pharm. Intervention in Cannabis UseR21DA019236 · NIDA · WAYNE STATE UNIVERSITY · PI LUNDAHL, LESLIE H · 2004 to 2005
$400k
NIDA NIH HHS R21 DA019236
6 · The paper itself

Abstract

aimsEvaluate magnitude and duration of subjective and physiologic responses to neutral and marijuana (MJ)-related cues in cannabis dependent volunteers.

methods33 volunteers (17 male) who met DSM-IV criteria for Cannabis Abuse or Dependence were exposed to neutral (first) then MJ-related visual, auditory, olfactory and tactile cues. Mood, drug craving and physiology were assessed at baseline, post-neutral, post-MJ and 15-min post MJ cue exposure to determine magnitude of cue- responses. For a subset of participants (n=15; 9 male), measures of craving and physiology were collected also at 30-, 90-, and 150-min post-MJ cue to examine duration of cue-effects.

resultsIn cue-response magnitude analyses, visual analog scale (VAS) items craving for, urge to use, and desire to smoke MJ, Total and Compulsivity subscale scores of the Marijuana Craving Questionnaire, anxiety ratings, and diastolic blood pressure (BP) were significantly elevated following MJ vs. neutral cue exposure. In cue-response duration analyses, desire and urge to use MJ remained significantly elevated at 30-, 90- and 150-min post MJ-cue exposure, relative to baseline and neutral cues.

conclusionsPresentation of polysensory MJ cues increased MJ craving, anxiety and diastolic BP relative to baseline and neutral cues. MJ craving remained elevated up to 150-min after MJ cue presentation. This finding confirms that carry-over effects from drug cue presentation must be considered in cue reactivity studies.

Indexed as

CravingCuesAdultAffectAnxietyCannabisDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleMarijuana AbuseMarijuana SmokingPhotic StimulationSurveys and QuestionnairesTime FactorsVolunteersCravingDurationMagnitudeMarijuana cue reactivity

Identifiers

PMID27436749
PMCPMC5113710
OpenAlexW2347012803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.