ArticleThe Plant cell2016
MEIOTIC F-BOX Is Essential for Male Meiotic DNA Double-Strand Break Repair in Rice.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 62 citations in OpenAlex.
- ZEP1 orchestrates template choice and crossover pathways to ensure meiotic genome integrity in rice.The EMBO journal · 2026Article
- The nuclear lamina protein NEMP1 regulates tapetal programmed cell death and pollen development in rice.aBIOTECH · 2026Article
- Plant tolerance mechanisms to DNA-damaging UV stress.Journal of experimental botany · 2025Review
- OsBRK1-mediated phosphorylation of OsPFN2 regulates meiotic spindle-actin assembly and rice fertility.Plant communications · 2025Article
- MORE FLORET1 Interacts with C-type Replication Protein A Complex and Regulates Male Meiosis in Rice.Rice (New York, N.Y.) · 2025Article
- Sequence-based analysis of the rice CAMTA family: haplotype and network analyses.Scientific reports · 2024Article
- BcSRC2 interacts with BcAPX4 to increase ascorbic acid content for responding ABA signaling and drought stress in pak choi.Horticulture research · 2024Article
- Structural Variants and Speciation: Multiple Processes at Play.Cold Spring Harbor perspectives in biology · 2024Review
- SCFNature communications · 2023Article
- Emerging roles of the ubiquitin-proteasome pathway in enhancing crop yield by optimizing seed agronomic traits.Plant cell reports · 2022Review
- SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.Nucleic acids research · 2022Article
- Natural variation in WHITE-CORE RATE 1 regulates redox homeostasis in rice endosperm to affect grain quality.The Plant cell · 2022Article
- FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis.iScience · 2022Article
- OsPRD2 is essential for double-strand break formation, but not spindle assembly during rice meiosis.Frontiers in plant science · 2022Article
- GIpred: a computational tool for prediction of GIGANTEA proteins using machine learning algorithm.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Gibberellins orchestrate panicle architecture mediated by DELLA-KNOX signalling in rice.Plant biotechnology journal · 2021Article
- Fanconi anemia ortholog FANCM regulates meiotic crossover distribution in plants.Plant physiology · 2021Article
- The Landscape of the Genomic Distribution and the Expression of the F-Box Genes Unveil Genome Plasticity in Hexaploid Wheat during Grain Development and in Response to Heat and Drought Stress.International journal of molecular sciences · 2021Article
- Ubiquitination in Plant Meiosis: Recent Advances and High Throughput Methods.Frontiers in plant science · 2021Review
- Exploiting Genic Male Sterility in Rice: From Molecular Dissection to Breeding Applications.Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
F-box proteins constitute a large superfamily in plants and play important roles in controlling many biological processes, but the roles of F-box proteins in male meiosis in plants remain unclear. Here, we identify the rice (Oryza sativa) F-box gene MEIOTIC F-BOX (MOF), which is essential for male meiotic progression. MOF belongs to the FBX subfamily and is predominantly active during leptotene to pachytene of prophase I. mof meiocytes display disrupted telomere bouquet formation, impaired pairing and synapsis of homologous chromosomes, and arrested meiocytes at late prophase I, followed by apoptosis. Although normal, programmed double-stranded DNA breaks (DSBs) form in mof mutants, foci of the phosphorylated histone variant γH2AX, a marker for DSBs, persist in the mutant, indicating that many of the DSBs remained unrepaired. The recruitment of Completion of meiosis I (COM1) and Radiation sensitive51C (RAD51C) to DSBs is severely compromised in mutant meiocytes, indicating that MOF is crucial for DSB end-processing and repair. Further analyses showed that MOF could physically interact with the rice SKP1-like Protein1 (OSK1), indicating that MOF functions as a component of the SCF E3 ligase to regulate meiotic progression in rice. Thus, this study reveals the essential role of an F-box protein in plant meiosis and provides helpful information for elucidating the roles of the ubiquitin proteasome system in plant meiotic progression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.