Evidence map›Paper›PMID 27436693›Full record

ArticleJournal of exposure science & environmental epidemiology2017

Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress.

Brent Altemose, Mark G Robson, Howard M Kipen, Pamela Ohman Strickland, Qingyu Meng, Jicheng Gong, Wei Huang, Guangfa Wang, David Q Rich, Tong Zhu and 1 more

Abstract read
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In one paragraph

Article in Journal of exposure science & environmental epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Longitudinal changes in cardiovascular disease-related proteins in welders.International archives of occupational and environmental health · 2024
    Article
  4. Article
  5. Article
  6. Particulate Matter Decreases Intestinal Barrier-Associated Proteins Levels in 3D Human Intestinal Model.International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Photochemical degradation of toluene in gas-phase under UV/visible light graphene oxide-TiOJournal of environmental health science & engineering · 2019
    Article
  9. Observational
  10. Article
  11. Article
  12. Detection and analysis of endogenous polar volatile organic compounds (PVOCs) in urine for human exposome research.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2019
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brent AltemoseSchool of Public Health, Rutgers University, Piscataway, New Jersey, USA.
Mark G RobsonSchool of Environmental and Biological Sciences, Rutgers University, New Brunswick, New Jersey, USA.
Howard M KipenEnvironmental and Occupational Sciences Institute (EOHSI), Rutgers University, Piscataway, New Jersey, USA.
Pamela Ohman StricklandSchool of Public Health, Rutgers University, Piscataway, New Jersey, USA.
Qingyu MengSchool of Public Health, Rutgers University, Piscataway, New Jersey, USA.
Jicheng GongNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, North Carolina, USA.
Wei HuangState Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, China.
Guangfa WangDepartment of Pulmonary Medicine, Peking University First Hospital, Beijing, China.
David Q RichSchool of Medicine and Dentistry, Department of Public Health Sciences, University of Rochester, Rochester, NY, USA.
Tong ZhuState Key Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing, China.
Junfeng ZhangNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, North Carolina, USA.

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ROBERT John LAUMBACH · 1988 to 2026
$47.4M
NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

Using data collected before, during, and after the 2008 Summer Olympic Games in Beijing, this study examines associations between biomarkers of blood coagulation (vWF, sCD62P and sCD40L), pulmonary inflammation (EBC pH, EBC nitrite, and eNO), and systemic oxidative stress (urinary 8-OHdG) with sources of air pollution identified utilizing principal component analysis and with concentrations of three aldehydes of health concern. Associations between the biomarkers and the air pollution source types and aldehydes were examined using a linear mixed effects model, regressing through seven lag days and controlling for ambient temperature, relative humidity, gender, and day of week for the biomarker measurements. The biomarkers for pulmonary inflammation, particularly EBC pH and eNO, were most consistently associated with vehicle and industrial combustion, oil combustion, and vegetative burning. The biomarkers for blood coagulation, particularly vWF and sCD62p, were most consistently associated with oil combustion. Systemic oxidative stress biomarker (8-OHdG) was most consistently associated with vehicle and industrial combustion. The associations of the biomarkers were generally not significant or consistent with secondary formation of pollutants and with the aldehydes. The findings support policies to control anthropogenic pollution sources rather than natural soil or road dust from a cardio-respiratory health standpoint.

Indexed as

8-Hydroxy-2'-DeoxyguanosineAdultAir PollutantsAir PollutionAldehydesBiomarkersBlood CoagulationChinaChromatography, High Pressure LiquidDeoxyguanosineEnvironmental MonitoringFemaleHumansHydrogen-Ion ConcentrationInflammationMale8-Hydroxy-2'-DeoxyguanosineAir PollutantsAldehydesBiomarkersDeoxyguanosineNitric OxideNitritesParticulate MatterVehicle Emissions

Identifiers

PMID27436693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.