Evidence map›Paper›PMID 27436187›Full record

ArticleBMC plant biology2016

Application of a library of near isogenic lines to understand context dependent expression of QTL for grain yield and adaptive traits in bread wheat.

Alba Farré, Liz Sayers, Michelle Leverington-Waite, Richard Goram, Simon Orford, Luzie Wingen, Cathy Mumford, Simon Griffiths

Open access · goldAbstract read
In one paragraph

Article in BMC plant biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
11.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alba FarréDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Liz SayersDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Michelle Leverington-WaiteDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Richard GoramDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Simon OrfordDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Luzie WingenDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Cathy MumfordDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK.
Simon GriffithsDepartment of Crop Genetics, John Innes Centre, Norwich, NR4 7UH, UK. Simon.griffiths@jic.ac.uk.ORCID 0000-0003-2435-7963
John Innes Centre · GB

Funding

Biotechnology and Biological Sciences Research Council BBS/E/J/000C0617Biotechnology and Biological Sciences Research Council BBS/E/J/000CA393
6 · The paper itself

Abstract

backgroundPrevious quantitative trait loci (QTLs) studies using the Avalon × Cadenza doubled haploid (DH) population identified eleven QTLs determining plant height, heading date and grain yield. The objectives of this study were: (i) to provide insight into the effects of these QTLs using reciprocal multiple near isogenic lines (NILs) with each pair of alleles compared in both parental backgrounds (Avalon or Cadenza), (ii) quantifying epistasis by looking at the background effects and (iii) predict favourable allelic combinations to develop superior genotypes adapted to a target environment.

resultsTo this aim, a library of 553 BC2 NILs and their recurrent parents were tested over two growing seasons (2012/2013 and 2013/2014). The results obtained in the present study validated the plant height, heading date and grain yield QTLs previously identified. Epistatic interactions were detected for the 6B QTL for plant height and heading date, 3A QTL for heading date and grain yield and 2A QTL for grain yield.

conclusionThe marker assisted backcrossing strategy used provided an efficient method of resolving QTL for key agronomic traits in wheat as Mendelian factors determining possible epistatic interactions. The study shows that these QTLs are amenable to marker assisted selection, fine mapping, future positional cloning, and physiological trait dissection.

Indexed as

Chromosomes, PlantHaploidyQuantitative Trait LociTriticumNear isogenic linesQTLWheatYield

Identifiers

PMID27436187
PMCPMC4952066
OpenAlexW2483196136

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.