Evidence map›Paper›PMID 27436150›Full record

ArticleEuropean journal of clinical nutrition2016

Hematological complications in anorexia nervosa.

E De Filippo, M Marra, F Alfinito, M L Di Guglielmo, P Majorano, G Cerciello, C De Caprio, F Contaldo, F Pasanisi

Open access · hybridAbstract read
In one paragraph

Article in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

E De FilippoDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
M MarraDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
F AlfinitoDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
M L Di GuglielmoDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
P MajoranoDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
G CercielloDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
C De CaprioDepartment of Clinical Medicine and Surgery 'Federico II' University, Naples, Italy.
F ContaldoInteruniversity Center for Obesity and Eating Disorders, Medical School, 'Federico II' University, Naples, Italy.
F PasanisiInteruniversity Center for Obesity and Eating Disorders, Medical School, 'Federico II' University, Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAnemia, leukopenia and, although less frequently, thrombocytopenia are possible hematological complications of anorexia nervosa considered strictly secondary to chronic malnutrition. This is a retrospective study on the prevalence of these disorders in a large cohort of 318 female patients with AN (20.4±5.6 years, body mass index (BMI) 15.9±1.6 kg/m SUBJECTS/

methodsPatients were studied on an outpatient basis after obtaining medical history, clinical examination, routine hematobiochemical and endocrine tests, electrocardiography, psychiatric interview and bioelectrical impedance analysis and, in particular, phase angle determination. All patients with other comorbidities, in particular with mean corpuscular volume <80 fl, were excluded for suspected genetic alteration in the synthesis of hemoglobin.

resultsHematologic data showed that 16.7% of patients had anemia, 7.9% neutropenia and 8.9% thrombocytopenia. These abnormalities were strictly related to the duration of illness (P=0.028), and to protein energy malnutrition, in particular, BMI and phase angle (P<0.001).

conclusionsOur study offers description of the incidence of hematologic defects in a selected and large sample of AN female patients, suggesting that its incidence is related to the degree and duration of protein energy malnutrition.

Indexed as

AdolescentAdultAnorexia NervosaChildCohort StudiesDietary ProteinsFemaleHematologic DiseasesHumansIncidenceItalyMiddle AgedPrevalenceRetrospective StudiesYoung AdultDietary Proteins

Identifiers

PMID27436150
PMCPMC5107965
OpenAlexW2487979091

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.